{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T17:10:07Z","timestamp":1756055407891,"version":"3.44.0"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,3,13]],"date-time":"2017-03-13T00:00:00Z","timestamp":1489363200000},"content-version":"vor","delay-in-days":71,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:p>Androgen insensitivity syndrome is the most common cause of male pseudohermaphroditism and the third most common cause of primary amenorrhea. This genetic alteration is a consequence of inherited defects on the X chromosome causing total or partial damage to the intrauterine virilization process due to functional abnormalities in the androgen receptors. The present report describes a 22\u2010year\u2010old patient with a female phenotype and a 46, XY karyotype, presenting with bilateral inguinal tumors. The tumors were surgically removed at the <jats:italic>Santa Casa de Miseric\u00f3rdia<\/jats:italic> Hospital in Vit\u00f3ria, Esp\u00edrito Santo, Brazil. Pathology revealed bilateral testicles with Sertoli cell tumors. According to the international literature, prophylactic gonadectomy following puberty is recommended due to the progressive risk of neoplastic transformation in the residual gonads.<\/jats:p>","DOI":"10.1155\/2017\/8357235","type":"journal-article","created":{"date-parts":[[2017,3,13]],"date-time":"2017-03-13T18:23:24Z","timestamp":1489429404000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Bilateral Sertoli Cell Tumors in a Patient with Androgen Insensitivity Syndrome"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8126-1450","authenticated-orcid":false,"given":"Roberta Fonseca","family":"de Souza","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janaina","family":"Pereira da Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Vieira Balla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo","family":"Neves Ferreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio","family":"Chamb\u00f4 Filho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,13]]},"reference":[{"key":"e_1_2_5_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(53)90359-7"},{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.9.7825"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(12)60071-3"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1590\/s0004-27302000000500010"},{"volume-title":"Clinical Gynecologic Endocrinology and Infertility","year":"2011","author":"Fritz M. 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