{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T07:15:39Z","timestamp":1770534939315,"version":"3.49.0"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"NHMRC","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100007811","name":"Sydney Medical School Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007811","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007028","name":"Leona M. and Harry B. Helmsley Charitable Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007028","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Diabetes Research"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p><jats:italic>Objectives<\/jats:italic>. To determine incidence, mortality, and clinical status of youth with diabetes at the Centro Vivir con Diabetes, Cochabamba, Bolivia, with support from International Diabetes Federation Life for a Child Program.<jats:italic>Methods<\/jats:italic>. Incidence\/mortality data analysis of all cases (&lt;25 year (y)) diagnosed January 2005\u2013February 2017 and cross-sectional data (December 2015).<jats:italic>Results<\/jats:italic>. Over 12.2 years, 144 cases with type 1 diabetes (T1D) were diagnosed; 43.1% were male. Diagnosis age was 0.3\u201322.2 y; peak was 11-12\u2009y. 11.1% were &lt;5\u2009y; 29.2%, 5\u2013&lt;10\u2009y; 43.1%, 10\u2013&lt;15\u2009y; 13.2%, 15\u2013&lt;20\u2009y; and 3.5%, 20\u2013&lt;25\u2009y. The youngest is being investigated for monogenic diabetes. Measured incidence in Cercado Province (Cochabamba Department) was 2.2\/100,000 children\u2009&lt;\u200915\u2009y\/y, with \u224880% ascertainment, giving total incidence of 2.7\/100,000 children\u2009&lt;\u200915\u2009y\/y. Two had died. Crude mortality rate was 2.3\/1000 patient years. Clinical data on 141 cases &lt;35\u2009y: mean\/median HbA1c was 8.5\/8.2% (69\/62\u2009mmol\/mol), levels higher in adolescents. Three were on renal replacement therapy; four others had substantial renal impairment. Elevated BMI, triglycerides, and cholesterol were common: 19.1%, 18.3%, and 39.1%, respectively.<jats:italic>Conclusions<\/jats:italic>. Bolivia has low T1D incidence. Reasonable glycemic control is being achieved despite limited resources; however, some have serious complications and adverse cardiovascular risk factor profiles. Further attention is needed for complications.<\/jats:p>","DOI":"10.1155\/2017\/8454757","type":"journal-article","created":{"date-parts":[[2017,8,29]],"date-time":"2017-08-29T21:02:33Z","timestamp":1504040553000},"page":"1-8","source":"Crossref","is-referenced-by-count":8,"title":["Incidence and Mortality Rates and Clinical Characteristics of Type 1 Diabetes among Children and Young Adults in Cochabamba, Bolivia"],"prefix":"10.1155","volume":"2017","author":[{"given":"Elizabeth","family":"Duarte G\u00f3mez","sequence":"first","affiliation":[{"name":"Centro Vivir con Diabetes, Av. 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