{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T05:31:56Z","timestamp":1784698316326,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2017]]},"abstract":"Purpose.<\/jats:italic> To analyze the errors associated to corneal power calculation using the keratometric approach in keratoconus eyes after accelerated corneal collagen crosslinking (CXL) surgery and to obtain a model for the estimation of an adjusted corneal refractive index n<\/mml:mi><\/mml:mrow>k<\/mml:mi><\/mml:mrow>a<\/mml:mi>d<\/mml:mi>j<\/mml:mi><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:mfenced><\/mml:math> minimizing such errors. Methods.<\/jats:italic> Potential differences (\u0394<\/mml:mi>P<\/mml:mi><\/mml:mrow>c<\/mml:mi><\/mml:mrow><\/mml:msub><\/mml:math>) among keratometric (P<\/mml:mi><\/mml:mrow>k<\/mml:mi><\/mml:mrow><\/mml:msub><\/mml:math>) and Gaussian corneal power (P<\/mml:mi><\/mml:mrow>c<\/mml:mi><\/mml:mrow>G<\/mml:mi>a<\/mml:mi>u<\/mml:mi>s<\/mml:mi>s<\/mml:mi><\/mml:mrow><\/mml:msubsup><\/mml:math>) were simulated. Three algorithms based on the use of n<\/mml:mi><\/mml:mrow>k<\/mml:mi><\/mml:mrow>a<\/mml:mi>d<\/mml:mi>j<\/mml:mi><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:msub><\/mml:math> for the estimation of an adjusted keratometric corneal power (P<\/mml:mi><\/mml:mrow>k<\/mml:mi><\/mml:mrow>a<\/mml:mi>d<\/mml:mi>j<\/mml:mi><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:msub><\/mml:math>) were developed. The agreement between P<\/mml:mi><\/mml:mrow>k<\/mml:mi>1.3375<\/mml:mn><\/mml:mrow><\/mml:mfenced><\/mml:mrow><\/mml:msub><\/mml:math> (keratometric power using the keratometric index of 1.3375), P<\/mml:mi><\/mml:mrow>c<\/mml:mi><\/mml:mrow>G<\/mml:mi>a<\/mml:mi>u<\/mml:mi>s<\/mml:mi>s<\/mml:mi><\/mml:mrow><\/mml:msubsup><\/mml:math>, and P<\/mml:mi><\/mml:mrow>k<\/mml:mi>a<\/mml:mi>d<\/mml:mi>j<\/mml:mi><\/mml:mrow><\/mml:msub><\/mml:math> was evaluated. The validity of the algorithm developed was investigated in 21 keratoconus eyes undergoing accelerated CXL. Results. <\/jats:italic>P<\/mml:mi><\/mml:mrow>k<\/mml:mi>1.3375<\/mml:mn><\/mml:mrow><\/mml:mfenced><\/mml:mrow><\/mml:msub><\/mml:math> overestimated corneal power between 0.3 and 3.2\u2009D in theoretical simulations and between 0.8 and 2.9\u2009D in the clinical study (\u0394<\/mml:mi>P<\/mml:mi><\/mml:mrow>c<\/mml:mi><\/mml:mrow><\/mml:msub><\/mml:math>). Three linear equations were defined for n<\/mml:mi><\/mml:mrow>k<\/mml:mi><\/mml:mrow>a<\/mml:mi>d<\/mml:mi>j<\/mml:mi><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:msub><\/mml:math> to be used for different ranges of r<\/jats:italic>1c<\/jats:sub>. In the clinical study, differences between P<\/mml:mi><\/mml:mrow>k<\/mml:mi><\/mml:mrow>a<\/mml:mi>d<\/mml:mi>j<\/mml:mi><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:msub><\/mml:math> and P<\/mml:mi><\/mml:mrow>c<\/mml:mi><\/mml:mrow>G<\/mml:mi>a<\/mml:mi>u<\/mml:mi>s<\/mml:mi>s<\/mml:mi><\/mml:mrow><\/mml:msubsup><\/mml:math> did not exceed \u00b10.8\u2009D n<\/mml:mi><\/mml:mrow>k<\/mml:mi><\/mml:mrow><\/mml:msub>=<\/mml:mo>1.3375<\/mml:mn><\/mml:math>. No statistically significant differences were found between P<\/mml:mi><\/mml:mrow>k<\/mml:mi><\/mml:mrow>a<\/mml:mi>d<\/mml:mi>j<\/mml:mi><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:msub><\/mml:math> and P<\/mml:mi><\/mml:mrow>c<\/mml:mi><\/mml:mrow>G<\/mml:mi>a<\/mml:mi>u<\/mml:mi>s<\/mml:mi>s<\/mml:mi><\/mml:mrow><\/mml:msubsup><\/mml:math> (p<\/mml:mi>><\/mml:mo>0.05<\/mml:mn><\/mml:math>) and P<\/mml:mi><\/mml:mrow>k<\/mml:mi>1.3375<\/mml:mn><\/mml:mrow><\/mml:mfenced><\/mml:mrow><\/mml:msub><\/mml:math> and P<\/mml:mi><\/mml:mrow>k<\/mml:mi><\/mml:mrow>a<\/mml:mi>d<\/mml:mi>j<\/mml:mi><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:msub><\/mml:math> (p<\/mml:mi><<\/mml:mo>0.001<\/mml:mn><\/mml:math>). Conclusions.<\/jats:italic> The use of the keratometric approach in keratoconus eyes after accelerated CXL can lead to significant clinical errors. These errors can be minimized with an adjusted keratometric approach.<\/jats:p>","DOI":"10.1155\/2017\/8529489","type":"journal-article","created":{"date-parts":[[2017,10,23]],"date-time":"2017-10-23T12:53:26Z","timestamp":1508763206000},"page":"1-8","source":"Crossref","is-referenced-by-count":4,"title":["Algorithm for Correcting the Keratometric Error in the Estimation of the Corneal Power in Keratoconus Eyes after Accelerated Corneal Collagen Crosslinking"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1546-4807","authenticated-orcid":true,"given":"David P.","family":"Pi\u00f1ero","sequence":"first","affiliation":[{"name":"Grupo de \u00d3ptica y Percepci\u00f3n Visual (GOPV), Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain"},{"name":"Department of Ophthalmology (OFTALMAR), Medimar International Hospital, Alicante, Spain"},{"name":"Fundaci\u00f3n para la Calidad Visual (FUNCAVIS), Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2150-3830","authenticated-orcid":true,"given":"Vicente J.","family":"Camps","sequence":"additional","affiliation":[{"name":"Grupo de \u00d3ptica y Percepci\u00f3n Visual (GOPV), Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esteban","family":"Caravaca-Arens","sequence":"additional","affiliation":[{"name":"Grupo de \u00d3ptica y Percepci\u00f3n Visual (GOPV), Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dolores","family":"de Fez","sequence":"additional","affiliation":[{"name":"Grupo de \u00d3ptica y Percepci\u00f3n Visual (GOPV), Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco J.","family":"Blanes-Momp\u00f3","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology (OFTALMAR), Medimar International Hospital, Alicante, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0b013e31823ac694"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2012.03.026"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31829e1eb5"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000048"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000190"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.3980\/j.issn.2222-3959.2014.02.21"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.4103\/2277-9175.151886"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2008.11.046"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.4103\/2008-322X.176894"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.4103\/0974-9233.151877"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20090512-08"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.12.046"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.09.013"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/s0039-6257(97)00119-7"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2007.06.016"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.313.7048.41"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3182904950"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000000141"}],"container-title":["Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2017\/8529489.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2017\/8529489.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2017\/8529489.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,10,23]],"date-time":"2017-10-23T12:53:26Z","timestamp":1508763206000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/joph\/2017\/8529489\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":18,"alternative-id":["8529489","8529489"],"URL":"https:\/\/doi.org\/10.1155\/2017\/8529489","relation":{},"ISSN":["2090-004X","2090-0058"],"issn-type":[{"value":"2090-004X","type":"print"},{"value":"2090-0058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}