{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T20:08:17Z","timestamp":1772136497578,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universidad T\u00e9cnica Paraticular de Loja","award":["PY1019"],"award-info":[{"award-number":["PY1019"]}]},{"name":"Universidad T\u00e9cnica Paraticular de Loja","award":["PY1620"],"award-info":[{"award-number":["PY1620"]}]},{"name":"Universidad T\u00e9cnica Paraticular de Loja","award":["PY1019"],"award-info":[{"award-number":["PY1019"]}]},{"name":"Universidad T\u00e9cnica Paraticular de Loja","award":["PY1620"],"award-info":[{"award-number":["PY1620"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>Human papillomavirus (HPV) is the primary infectious agent for the development of cervical cancer, although the presence of the virus alone is insufficient for viral development and proliferation; this can be attributed to the increase in potential oncogenic risk, along with other risk factors. In the present investigation, the prevalence of high-risk HPV was determined from samples of premalignant or malignant cervical cytology in women from the southern region of Ecuador. The kit we used was able to detect genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and 59. In addition, 64.5% of the analyzed samples were positive for HPV, with genotypes 16 and 18 being the most prevalent (16 was detected in 148 samples and 18 in 108). Genotypes 58 and 51 were the third most frequent simple and multiple infections, respectively. The data are very similar to those obtained worldwide, suggesting that the strategy of sex education, and the use of vaccines as primary prevention agents, could significantly decrease the incidence and mortality rate of cervical cancer in the southern region of Ecuador.<\/jats:p>","DOI":"10.1155\/2017\/8572065","type":"journal-article","created":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T21:06:40Z","timestamp":1498165600000},"page":"1-7","source":"Crossref","is-referenced-by-count":10,"title":["Prevalence of High-Risk Genotypes of Human Papillomavirus: Women Diagnosed with Premalignant and Malignant Pap Smear Tests in Southern Ecuador"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1125-7592","authenticated-orcid":true,"given":"Paola","family":"Dalgo Aguilar","sequence":"first","affiliation":[{"name":"Departamento de Ciencias de la Salud, Secci\u00f3n Gen\u00e9tica Humana, Microbiolog\u00eda y Bioqu\u00edmica Cl\u00ednica, Universidad T\u00e9cnica Particular de Loja, Loja, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cisne","family":"Loj\u00e1n Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Sociedad de Lucha Contra el C\u00e1ncer, Hospital SOLCA N\u00facleo de Loja, Loja, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"C\u00f3rdova Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias de la Salud, Secci\u00f3n Gen\u00e9tica Humana, Microbiolog\u00eda y Bioqu\u00edmica Cl\u00ednica, Universidad T\u00e9cnica Particular de Loja, Loja, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Acurio P\u00e1ez","sequence":"additional","affiliation":[{"name":"Sociedad de Lucha Contra el C\u00e1ncer, Hospital SOLCA N\u00facleo de Loja, Loja, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Paulina","family":"Ar\u00e9valo","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias de la Salud, Secci\u00f3n Gen\u00e9tica Humana, Microbiolog\u00eda y Bioqu\u00edmica Cl\u00ednica, Universidad T\u00e9cnica Particular de Loja, Loja, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Bobokova","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias de la Salud, Secci\u00f3n Gen\u00e9tica Humana, Microbiolog\u00eda y Bioqu\u00edmica Cl\u00ednica, Universidad T\u00e9cnica Particular de Loja, Loja, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","journal-title":"International Agency for Research on Cancer"},{"key":"3","year":"2010"},{"issue":"12","key":"4","first-page":"5826","volume":"7","year":"2014","journal-title":"Int J Exp Med"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1080\/03630242.2014.979970"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600688"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2014.15.23.10061"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2004.12.008"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.4067\/S0034-98872014000800012"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2014.15.17.7333"},{"issue":"2","key":"11","first-page":"81","year":"2012","journal-title":"Sexolog\u03c6a Medica"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/S1995-7645(14)60217-0"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.05.064"},{"key":"14","year":"August 2014","journal-title":"Med J Malaysia"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2006.05.115"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.55.4.244"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.4067\/S0716-10182013000200009"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0109301"},{"issue":"11","key":"19","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.4067\/S0034-98872010001200001","volume":"138","year":"2010","journal-title":"Rev Med Chil"},{"key":"20","first-page":"2013","year":"2013","journal-title":"Obstet Gynecol Int"},{"issue":"1","key":"21","first-page":"32","volume":"22","year":"2010","journal-title":"Rev Oncol Y Hematol Venez"},{"issue":"3","key":"22","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1128\/JCM.35.3.791-795.1997","volume":"35","year":"1997","journal-title":"J Clin Microbiol"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.2174\/1874372200903020090"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.16.1.1-17.2003"},{"key":"25","first-page":"61","volume":"3","year":"2014","journal-title":"International Journal of Molecular and Cellular Medicine"},{"issue":"11","key":"26","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/S1470-2045(10)70230-8","volume":"11","year":"2010","journal-title":"Lancet Oncol"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.4161\/hv.28712"},{"issue":"3","key":"28","first-page":"234","volume":"24","year":"2007","journal-title":"Revista Peruana de Medicina Experimental y Salud P\u00fablica"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dji187"},{"issue":"1","key":"31","doi-asserted-by":"crossref","first-page":"7","DOI":"10.17533\/udea.rfnsp.10311","volume":"30","year":"2012","journal-title":"Revista Facultad Nacional de Salud P\u00fablica"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.3233\/CBM-2009-0107"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.24310"},{"issue":"1","key":"34","doi-asserted-by":"crossref","first-page":"79","DOI":"10.18537\/mskn.06.01.07","volume":"6","year":"2015","journal-title":"Maskana"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2009000700007"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1086\/657321"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025493"},{"issue":"2","key":"38","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1590\/S0074-02762010000200006","volume":"105","year":"2010","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"4","key":"39","first-page":"137","volume":"69","year":"2001","journal-title":"Ginecol Obs Mex"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21317"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1590\/1980-5497201600010014"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6601024"},{"issue":"3","key":"44","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1136\/sextrans-2011-050306","volume":"88","year":"2012","journal-title":"Sex Transm Infect [Internet]"},{"issue":"1","key":"45","first-page":"54","volume":"10","year":"2013","journal-title":"NIH Public Access. Sex Transm Dis"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69479-8"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa053284"}],"container-title":["Infectious Diseases in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/2017\/8572065.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/2017\/8572065.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/2017\/8572065.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T23:11:30Z","timestamp":1750374690000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/idog\/2017\/8572065\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":44,"alternative-id":["8572065","8572065"],"URL":"https:\/\/doi.org\/10.1155\/2017\/8572065","relation":{},"ISSN":["1064-7449","1098-0997"],"issn-type":[{"value":"1064-7449","type":"print"},{"value":"1098-0997","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}