{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:41:52Z","timestamp":1770223312060,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>Diarrhea is one of the most common symptoms in common variable immunodeficiency, but neurologic manifestations are rare. We presented a 50-year-old woman with recurrent diarrhea and severe weight loss that developed a posterior cord syndrome. Endoscopy found a duodenal villous blunting, intraepithelial lymphocytosis, and lack of plasma cells and magnetic resonance imaging of the spine was normal. Laboratory assays confirmed common variable immunodeficiency syndrome and showed low levels of trace elements (copper and zinc). Treatment was initiated with parenteral replacement of trace elements and intravenous human immunoglobulin and the patient improved clinically. In conclusion, physicians must be aware that gastrointestinal and neurologic disorders may be related to each other and remember to request trace elements laboratory assessment.<\/jats:p>","DOI":"10.1155\/2017\/9870305","type":"journal-article","created":{"date-parts":[[2017,3,5]],"date-time":"2017-03-05T16:01:12Z","timestamp":1488729672000},"page":"1-5","source":"Crossref","is-referenced-by-count":2,"title":["Posterior Cord Syndrome and Trace Elements Deficiency as an Uncommon Presentation of Common Variable Immunodeficiency"],"prefix":"10.1155","volume":"2017","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0494-5303","authenticated-orcid":true,"given":"Yuri","family":"Silva Macedo","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine, Hospital Universit\u00e1rio Ant\u00f4nio Pedro (HUAP), Universidade Federal Fluminense (UFF), Rua Marqu\u00eas de Paran\u00e1 303, 7\u00b0 Andar, Centro, 24033-90 Niter\u00f3i, RJ, 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