{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T20:30:06Z","timestamp":1740169806978,"version":"3.37.3"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p><jats:italic>Objectives.<\/jats:italic> The aim of this study is to assess the feasibility and clinical outcome of transcatheter aortic valve replacement (TAVR) using aortic valve predilatation (AVPD) with a small, nonocclusive balloon.<jats:italic> Background.<\/jats:italic> Balloon aortic valvuloplasty (BAV) under rapid pacing is generally performed in TAVR to ensure the passage and sufficient deployment of the prosthesis in the stenotic AV. BAV may cause serious complications, such as left ventricular stunning or cerebrovascular embolism.<jats:italic> Methods.<\/jats:italic> A cohort of 50 consecutive patients with severe aortic stenosis underwent transfemoral TAVR with the Edwards Sapien 3-heart valve. All patients underwent AVPD with a small, nonocclusive balloon (12 \u00d7 60 or 14 \u00d7 60\u2009mm) without rapid pacing. Procedural data and clinical outcomes were analyzed.<jats:italic> Results.<\/jats:italic> The mean age of the cohort was <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn fontstyle=\"italic\">81<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">6<\/mml:mn><\/mml:math> years and the mean logistic EuroSCORE (European System for Cardiac Operative Risk Evaluation) was <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn fontstyle=\"italic\">13<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">9<\/mml:mn><\/mml:math>. Crossing the AV and prosthesis implantation was successful in all cases. The postprocedural mean AV gradient was <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mn fontstyle=\"italic\">12<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">5<\/mml:mn><\/mml:math>\u2009mmHg. There were no cases of aortic regurgitation \u2265 grade 2. No periprocedural stroke occurred. One patient (2%) with chronic atrial fibrillation displayed a transient Wernicke aphasia occurring more than 24 hours after TAVR. Mortality was 0% at 30 days after procedure.<jats:italic> Conclusion.<\/jats:italic> In TAVR, AVPD with a small, nonocclusive balloon can be safely performed. By avoiding rapid pacing, this technique may be a valid alternative to traditional BAV. Whether or not the use of APVD without rapid pacing translates into less periprocedural complications needs to be assessed in future studies.<\/jats:p>","DOI":"10.1155\/2018\/1080597","type":"journal-article","created":{"date-parts":[[2018,4,30]],"date-time":"2018-04-30T19:30:47Z","timestamp":1525116647000},"page":"1-6","source":"Crossref","is-referenced-by-count":7,"title":["Aortic Valve Predilatation with a Small Balloon, without Rapid Pacing, prior to Transfemoral Transcatheter Aortic Valve Replacement"],"prefix":"10.1155","volume":"2018","author":[{"given":"Anupama","family":"Shivaraju","sequence":"first","affiliation":[{"name":"Deutsches Herzzentrum M\u00fcnchen, Department for Cardiovascular Diseases, Technische Universit\u00e4t M\u00fcnchen, Lazarettstr. 36, 80636 Munich, Germany"},{"name":"Department of Cardiology, Advocate Christ Medical Center, 4440 W. 95th Street, Oak Lawn, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Thilo","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Klinikum Augsburg, Herzzentrum Augsburg-Schwaben, Stenglinstr. 2, 86156 Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neal","family":"Sawlani","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Advocate Christ Medical Center, 4440 W. 95th Street, Oak Lawn, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilka","family":"Ott","sequence":"additional","affiliation":[{"name":"Deutsches Herzzentrum M\u00fcnchen, Department for Cardiovascular Diseases, Technische Universit\u00e4t M\u00fcnchen, Lazarettstr. 36, 80636 Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heribert","family":"Schunkert","sequence":"additional","affiliation":[{"name":"Deutsches Herzzentrum M\u00fcnchen, Department for Cardiovascular Diseases, Technische Universit\u00e4t M\u00fcnchen, Lazarettstr. 36, 80636 Munich, Germany"},{"name":"Deutsches Zentrum f\u00fcr Herz- und Kreislaufforschung (DZHK), Munich Heart Alliance, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"von Scheidt","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Klinikum Augsburg, Herzzentrum Augsburg-Schwaben, Stenglinstr. 2, 86156 Augsburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adnan","family":"Kastrati","sequence":"additional","affiliation":[{"name":"Deutsches Herzzentrum M\u00fcnchen, Department for Cardiovascular Diseases, Technische Universit\u00e4t M\u00fcnchen, Lazarettstr. 36, 80636 Munich, Germany"},{"name":"Deutsches Zentrum f\u00fcr Herz- und Kreislaufforschung (DZHK), Munich Heart Alliance, Munich, 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