{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T19:40:41Z","timestamp":1790538041742,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,8,14]],"date-time":"2018-08-14T00:00:00Z","timestamp":1534204800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2018,8,14]]},"abstract":"<jats:p>Antimicrobial resistance in Gram-negative bacteria, particularly Enterobacteriaceae, has become a leading cause of morbidity and mortality and a serious public health concern. Gram-negative bacteria carrying extended-spectrum beta-lactamase (ESBL) enzymes now represent a significant proportion of all bacteria isolated from different countries worldwide. Furthermore, the increasing number of isolates carrying carbapenemases in recent years includes multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) bacteria. Here, we describe what, to our knowledge, is the first case of a patient with a prosthetic joint infection from carbapenemase-resistant <jats:italic>Klebsiella pneumoniae<\/jats:italic> (CRKP) successfully treated with ceftazidime-avibactam in Italy.<\/jats:p>","DOI":"10.1155\/2018\/1854805","type":"journal-article","created":{"date-parts":[[2018,8,14]],"date-time":"2018-08-14T19:30:40Z","timestamp":1534275040000},"page":"1-5","source":"Crossref","is-referenced-by-count":7,"title":["Prosthetic Joint Infection from Carbapenemase-Resistant <i>Klebsiella pneumoniae<\/i> Successfully Treated with Ceftazidime-Avibactam"],"prefix":"10.1155","volume":"2018","author":[{"given":"A.","family":"Schimmenti","sequence":"first","affiliation":[{"name":"Dipartimento di Scienze Clinico-Chirurgiche, Diagnostiche e Pediatriche, Unit\u00e0 di Malattie Infettive e Tropicali ed Epatologia, Universit\u00e0 di Pavia, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Brunetti","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Clinico-Chirurgiche, Diagnostiche e Pediatriche, Unit\u00e0 di Malattie Infettive e Tropicali ed Epatologia, Universit\u00e0 di Pavia, Pavia, Italy"},{"name":"Unit\u00e0 di Malattie Infettive e Tropicali, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Seminari","sequence":"additional","affiliation":[{"name":"Unit\u00e0 di Malattie Infettive e Tropicali, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Mariani","sequence":"additional","affiliation":[{"name":"Microbiologia e Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Cambieri","sequence":"additional","affiliation":[{"name":"Microbiologia e Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3223-1658","authenticated-orcid":true,"given":"P.","family":"Orsolini","sequence":"additional","affiliation":[{"name":"Unit\u00e0 di Malattie Infettive e Tropicali, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy"},{"name":"Dipartimento di Medicina Interna e Terapia Medica, Universit\u00e0 di Pavia, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2017.06.007"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-018-0902-x"},{"key":"3","year":"2017"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00099-14"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-017-0235-7"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1017\/s0950268813002975"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2015.09.015"},{"key":"8","year":"2018"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00883-17"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.2147\/tcrm.s120811"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-008588"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2011.12.014"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-010-0950-y"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2007.12.018"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2014.01.028"}],"container-title":["Case Reports in Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2018\/1854805.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2018\/1854805.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2018\/1854805.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,8,14]],"date-time":"2018-08-14T19:30:41Z","timestamp":1534275041000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criid\/2018\/1854805\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,14]]},"references-count":16,"alternative-id":["1854805","1854805"],"URL":"https:\/\/doi.org\/10.1155\/2018\/1854805","relation":{},"ISSN":["2090-6625","2090-6633"],"issn-type":[{"value":"2090-6625","type":"print"},{"value":"2090-6633","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,14]]}}}