{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:03:03Z","timestamp":1740164583840,"version":"3.37.3"},"reference-count":11,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T00:00:00Z","timestamp":1528070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Pathology"],"published-print":{"date-parts":[[2018,6,4]]},"abstract":"<jats:p><jats:italic>Introduction.<\/jats:italic> Renal cell carcinoma is the third most common urogenital cancer. In some patients, it can metastasize to distant organs. Metastasis to the vagina is extremely rare.<jats:italic> Case Presentation.<\/jats:italic> A 54-year-old female with unremarkable history presented to the clinic with a chief complaint of vaginal bleeding. Further examination identified a pedunculated mass on the vaginal wall. Histologic examination revealed a metastatic clear cell renal cell carcinoma. Radiological studies then revealed a left renal mass and bilateral adrenal masses. The patient underwent a nephrectomy, adrenalectomy, and resection of the vaginal mass. The mass in the vagina has since recurred.<jats:italic> Conclusion. <\/jats:italic>We report the first known case of vaginal metastasis as initial presentation of a renal cell carcinoma with rhabdoid features. Postmenopausal women with renal cell carcinoma who present with vaginal bleeding should undergo a thorough inspection of the vaginal wall for the potential of metastatic neoplasms.<\/jats:p>","DOI":"10.1155\/2018\/2109279","type":"journal-article","created":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T19:30:38Z","timestamp":1528140638000},"page":"1-4","source":"Crossref","is-referenced-by-count":4,"title":["Vaginal Bleeding as Initial Presentation of an Aggressive Renal Cell Carcinoma: A Case Report and Review of the Literature"],"prefix":"10.1155","volume":"2018","author":[{"given":"Antonio R.","family":"Jimenez","sequence":"first","affiliation":[{"name":"Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77550, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria del Mar","family":"Rivera Rolon","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77550, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Eyzaguirre","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77550, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4423-0313","authenticated-orcid":true,"given":"Cecilia","family":"Clement","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77550, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3233\/CBM-2011-0176"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1309\/YR7P42XUVQHPHDWL"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)56678-1"},{"issue":"9","key":"4","first-page":"1793","volume":"5126","year":"2013","journal-title":"Chinese Medical Journal"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0000000000000466"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0000000000000253"},{"key":"7","first-page":"62","volume":"14","year":"2013","journal-title":"The Pan African Medical Journal"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2003.11.046"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.3109\/00365599009180868"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000251"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1113205"}],"container-title":["Case Reports in Pathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2018\/2109279.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2018\/2109279.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2018\/2109279.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T19:30:40Z","timestamp":1528140640000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cripa\/2018\/2109279\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,4]]},"references-count":11,"alternative-id":["2109279","2109279"],"URL":"https:\/\/doi.org\/10.1155\/2018\/2109279","relation":{},"ISSN":["2090-6781","2090-679X"],"issn-type":[{"type":"print","value":"2090-6781"},{"type":"electronic","value":"2090-679X"}],"subject":[],"published":{"date-parts":[[2018,6,4]]}}}