{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T14:49:01Z","timestamp":1788878941351,"version":"build-2803163510"},"reference-count":65,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,1,11]],"date-time":"2018-01-11T00:00:00Z","timestamp":1515628800000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Dilla University","award":["AgNR\/AnSc\/2015\/10"],"award-info":[{"award-number":["AgNR\/AnSc\/2015\/10"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To evaluate the <jats:italic>in vitro<\/jats:italic> antibacterial activities of five plant extracts which have been used as traditional medicines by local healers against three multidrug resistant bacteria, namely, <jats:italic>Staphylococcus aureus<\/jats:italic>, <jats:italic>Escherichia coli<\/jats:italic>, and <jats:italic>Pseudomonas aeruginosa<\/jats:italic>. <jats:italic>Results<\/jats:italic>. The highest mean zone of inhibition (4.66\u2009mm) was recorded from methanol extract of <jats:italic>Calpurnia aurea<\/jats:italic> (Ait.) Benth. at a concentration of 200\u2009mg\/ml against <jats:italic>S. aureus<\/jats:italic>, followed by <jats:italic>Croton macrostachyus<\/jats:italic> Del. (4.43\u2009mm) at the same dose and solvent for the same bacterial species, while methanol and chloroform extracts of <jats:italic>E. brucei<\/jats:italic> Schwein. did not inhibit growth of any bacterial species. The lowest value (100\u2009<jats:italic>\u03bc<\/jats:italic>g\/ml) of minimum inhibitory concentration (MIC) was observed from both methanol and chloroform extracts of <jats:italic>C. aurea<\/jats:italic> (Ait.) Benth. against all the three bacteria. The results of the positive control had no statistically significant difference (<jats:italic>P<\/jats:italic> &gt; 0.05) when compared with crude extracts of <jats:italic>C. aurea<\/jats:italic> (Ait.) Benth. at concentration of 200\u2009mg\/ml against <jats:italic>S. aureus<\/jats:italic>. <jats:italic>Conclusion<\/jats:italic>. The results of the present study support the traditional uses of these medicinal plants by the local healers. Except <jats:italic>Erythrina brucei<\/jats:italic> Schwein., all the plants investigated in this study exhibited antibacterial activities against the test bacterial species. Further researches are needed to be conducted to evaluate efficacy of these medicinal plant species on other microbes in different agroecological settings and their safety levels as well as their phytochemical compositions.<\/jats:p>","DOI":"10.1155\/2018\/2950758","type":"journal-article","created":{"date-parts":[[2018,1,11]],"date-time":"2018-01-11T23:33:39Z","timestamp":1515713619000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Antibacterial Activities of Five Medicinal Plants in Ethiopia against Some Human and Animal Pathogens"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3115-8121","authenticated-orcid":false,"given":"Gebremedhin","family":"Romha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birhanu","family":"Admasu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsegaye","family":"Hiwot Gebrekidan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3382-2580","authenticated-orcid":false,"given":"Hailelule","family":"Aleme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gebreyohans","family":"Gebru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,11]]},"reference":[{"key":"e_1_2_11_1_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.1.4.377"},{"key":"e_1_2_11_2_2","volume-title":"Bacteria Associated with Foodborne Diseases","author":"Institute of Food Technologtiss"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.00302"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.00264"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1172\/jci200318535"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1805.111153"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.009142-0"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"key":"e_1_2_11_9_2","first-page":"1039","article-title":"Update on bacterial nosocomial infections","volume":"16","author":"Bereket W.","year":"2012","journal-title":"European Review for Medical and Pharmacological Sciences"},{"key":"e_1_2_11_10_2","unstructured":"National strategy for combating antibiotic - resistant bacteria 2014 https:\/\/www.cdc.gov\/drugresistance\/pdf\/carb_national_strategy.pdf."},{"key":"e_1_2_11_11_2","first-page":"35","article-title":"Controle microbi\u00f3gico de produtos fitoter\u00e1picos","volume":"31","author":"Santos","year":"1995","journal-title":"Revista De Farmacia E Bioquimica"},{"key":"e_1_2_11_12_2","first-page":"9","article-title":"Antimicrobialactivity of leaf extracts of Jurineadolomiaea plant against clinical and phytopathogenic bacteria","volume":"24","author":"In Dwivedi S. 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