{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:30:48Z","timestamp":1790681448783,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,7,2]],"date-time":"2018-07-02T00:00:00Z","timestamp":1530489600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["DK107339-03"],"award-info":[{"award-number":["DK107339-03"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["RX000889-06"],"award-info":[{"award-number":["RX000889-06"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006380","name":"Rehabilitation Research and Development Service","doi-asserted-by":"publisher","award":["DK107339-03"],"award-info":[{"award-number":["DK107339-03"]}],"id":[{"id":"10.13039\/100006380","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006380","name":"Rehabilitation Research and Development Service","doi-asserted-by":"publisher","award":["RX000889-06"],"award-info":[{"award-number":["RX000889-06"]}],"id":[{"id":"10.13039\/100006380","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006379","name":"Office of Research and Development","doi-asserted-by":"publisher","award":["DK107339-03"],"award-info":[{"award-number":["DK107339-03"]}],"id":[{"id":"10.13039\/100006379","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006379","name":"Office of Research and Development","doi-asserted-by":"publisher","award":["RX000889-06"],"award-info":[{"award-number":["RX000889-06"]}],"id":[{"id":"10.13039\/100006379","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Veterans Health Administration","award":["DK107339-03"],"award-info":[{"award-number":["DK107339-03"]}]},{"name":"Veterans Health Administration","award":["RX000889-06"],"award-info":[{"award-number":["RX000889-06"]}]},{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","award":["DK107339-03"],"award-info":[{"award-number":["DK107339-03"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","award":["RX000889-06"],"award-info":[{"award-number":["RX000889-06"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Diabetes Research"],"published-print":{"date-parts":[[2018,7,2]]},"abstract":"<jats:p>In this study, we wanted to extend our investigation of the efficacy of fish oil with or without salsalate on vascular and neural complications using a type 2 diabetic rat model. Four weeks after the onset of hyperglycemia, diabetic rats were treated via the diet with 3 different amounts of menhaden oil with or without salsalate for 12 weeks. Afterwards, vascular reactivity of epineurial arterioles and neuropathy-related endpoints were examined. The addition of salsalate to high-fat diets enriched with 10% or 25% kcal of menhaden oil protected vascular reactivity to acetylcholine and calcium gene-related peptide, motor and sensory nerve conduction velocity, thermal nociception, intraepidermal nerve fiber density, and cornea sensitivity to a greater extent than 10% or 25% menhaden oil alone. Vascular and neural function was maximally protected with diet containing 45% kcal as menhaden oil, and adding salsalate did not provide any additional benefit. Salsalate alone in the high-fat diet of diabetic rats provided minimal protection\/improvement of vascular and neural dysfunction. These studies imply that dietary salsalate in combination with lower amounts of menhaden oil can provide greater benefit toward diabetes-induced vascular and neural impairment than menhaden oil alone.<\/jats:p>","DOI":"10.1155\/2018\/2967127","type":"journal-article","created":{"date-parts":[[2018,7,2]],"date-time":"2018-07-02T19:59:45Z","timestamp":1530561585000},"page":"1-9","source":"Crossref","is-referenced-by-count":23,"title":["Effect of Dietary Content of Menhaden Oil with or without Salsalate on Neuropathic Endpoints in High-Fat-Fed\/Low-Dose Streptozotocin-Treated Sprague Dawley Rats"],"prefix":"10.1155","volume":"2018","author":[{"given":"Eric P.","family":"Davidson","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence J.","family":"Coppey","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2963-1717","authenticated-orcid":true,"given":"Hanna","family":"Shevalye","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Obrosov","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7737-5554","authenticated-orcid":true,"given":"Mark A.","family":"Yorek","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA"},{"name":"Department of Veterans Affairs Iowa City Health Care System, Iowa City, IA 52246, USA"},{"name":"Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA 52242, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.02.005"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-53480-4.00009-6"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/950517"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00718.2014"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/5905891"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00224.2015"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.4172\/2155-9562.1000453"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2017.09.015"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.14740\/jocmr3362w"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1186\/s40169-017-0153-6"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-015-4091-z"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1021\/cr100396c"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1038\/nature13479"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1003603"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000001728"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.5.1417"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-159-1-201307020-00003"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-011-0329-2"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(90)90465-D"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2011.12.003"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.11-8806"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1444-0938.2012.00729.x"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-003-1086-8"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-13794"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-19435"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1155\/EDR.2000.131"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1080\/15438600490486732"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1053\/meta.2000.17721"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2005.05.004"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20991"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2015.06.009"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.2337\/db09-1761"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2017.08.004"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0179063"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1900\/RDS.2015.12.13"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.257"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-12075"}],"container-title":["Journal of Diabetes Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jdr\/2018\/2967127.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jdr\/2018\/2967127.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jdr\/2018\/2967127.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,7,2]],"date-time":"2018-07-02T19:59:57Z","timestamp":1530561597000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/jdr\/2018\/2967127\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,2]]},"references-count":37,"alternative-id":["2967127","2967127"],"URL":"https:\/\/doi.org\/10.1155\/2018\/2967127","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.733760706.793556085","asserted-by":"object"}]},"ISSN":["2314-6745","2314-6753"],"issn-type":[{"value":"2314-6745","type":"print"},{"value":"2314-6753","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,2]]}}}