{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T23:53:45Z","timestamp":1785542025482,"version":"3.56.0"},"reference-count":44,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,7,22]],"date-time":"2018-07-22T00:00:00Z","timestamp":1532217600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parkinson's Disease"],"published-print":{"date-parts":[[2018,7,22]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. Deep brain stimulation (DBS) surgery has increasingly been performed for the treatment of movement disorders and is associated with a wide array of complications. We aimed to present our experience and discuss strategies to minimize adverse events in light of this contemporary series and others in the literature. <jats:italic>Methods<\/jats:italic>. A retrospective chart review was conducted to collect data on age, sex, indication, operation date, surgical technique, and perioperative and late complications. <jats:italic>Results<\/jats:italic>. A total of 181 patients (113 males, 68 females) underwent DBS implantation surgery (359 leads) in the past six years. Indications and targets were as follows: Parkinson\u2019s disease (STN) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>159<\/mml:mn><\/mml:mrow><\/mml:math>), dystonia (GPi) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>13<\/mml:mn><\/mml:mrow><\/mml:math>), and essential tremor (Vim) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>9<\/mml:mn><\/mml:mrow><\/mml:math>). Mean age was 55.2\u2009\u00b1\u200911.7 (range 9\u201374) years. Mean follow-up duration was 3.4\u2009\u00b1\u20091.6 years. No mortality or permanent morbidity was observed. Major perioperative complications were confusion (6.6%), intracerebral hemorrhage (2.2%), stroke (1.1%), and seizures (1.1%). Long-term adverse events included wound (7.2%), mostly infection, and hardware-related (5.5%) complications. Among several factors, only surgical experience was found to be related with overall complication rates (early period: 31% versus late period: 10%; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>). <jats:italic>Conclusion<\/jats:italic>. The rates of both early and late complications of DBS surgery are acceptably low and decrease significantly with cumulative experience.<\/jats:p>","DOI":"10.1155\/2018\/3056018","type":"journal-article","created":{"date-parts":[[2018,7,22]],"date-time":"2018-07-22T19:30:56Z","timestamp":1532287856000},"page":"1-7","source":"Crossref","is-referenced-by-count":15,"title":["Experience Reduces Surgical and Hardware-Related Complications of Deep Brain Stimulation Surgery: A Single-Center Study of 181 Patients Operated in Six Years"],"prefix":"10.1155","volume":"2018","author":[{"given":"Mehmet","family":"Sorar","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Diskapi Yildirim Beyazit Training and Research Hospital, Health Sciences University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahin","family":"Hanalioglu","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Diskapi Yildirim Beyazit Training and 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Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7113-9830","authenticated-orcid":true,"given":"Hayri","family":"Kertmen","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Diskapi Yildirim Beyazit Training and Research Hospital, Health Sciences University, Ankara, 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