{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T05:46:47Z","timestamp":1750916807558,"version":"3.37.3"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology Research and Practice"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Nontyphoidal <jats:italic>Salmonella<\/jats:italic> infection is a common cause for acute bacterial gastroenteritis in children in China. There have been no reports of the prevalence of lactose intolerance or food allergies in children with nontyphoidal <jats:italic>Salmonella<\/jats:italic> infection. The aim of this study was to characterize nontyphoidal <jats:italic>Salmonella<\/jats:italic> gastroenteritis in a tertiary children\u2019s hospital and evaluate clinical presentation, lactose intolerance, and food allergies in children with prolonged nontyphoidal <jats:italic>Salmonella<\/jats:italic> gastroenteritis. <jats:italic>Methods<\/jats:italic>. A retrospective case-series analysis was carried out in a tertiary children\u2019s hospital in Guangzhou, China. We included all infants and children who were diagnosed with nontyphoidal <jats:italic>Salmonella<\/jats:italic> gastroenteritis between 1 January 2014 and 31 December 2016. Patients\u2019 clinical features, feeding patterns, laboratory tests, and treatment outcomes were reviewed. <jats:italic>Results<\/jats:italic>. A total of 142 infants and children were diagnosed with nontyphoidal <jats:italic>Salmonella<\/jats:italic> gastroenteritis. 52.1% of cases occurred in infants\u2009\u2264\u200912 months of age and the majority (89.4%) in children younger than 3 years old. The most common symptoms were diarrhea (100%), fever (62%), and vomiting (18.3%). <jats:italic>Salmonella<\/jats:italic> Typhimurium was the predominant serotype, accounting for 82.4%. 91.5% of patients were treated with antibiotics. Forty-one (28.9%) and 9 (6.3%) children improved with a lactose-free diet and hypoallergenic formula, respectively, when diarrhea persisted for more than a week. <jats:italic>Conclusions<\/jats:italic>. <jats:italic>Salmonella<\/jats:italic> Typhimurium was the predominant serotype. Most patients with nontyphoidal <jats:italic>Salmonella<\/jats:italic> gastroenteritis were younger than 3 years old. Lactose intolerance occurred frequently in children with nontyphoidal <jats:italic>Salmonella<\/jats:italic> gastroenteritis and dietary modification should be considered when diarrhea is persistent and prolonged.<\/jats:p>","DOI":"10.1155\/2018\/3097468","type":"journal-article","created":{"date-parts":[[2018,3,4]],"date-time":"2018-03-04T18:31:05Z","timestamp":1520188265000},"page":"1-4","source":"Crossref","is-referenced-by-count":5,"title":["Nontyphoidal <i>Salmonella<\/i> Gastroenteritis in a Tertiary Children\u2019s Hospital in Southern China: Characteristics and Dietary Considerations"],"prefix":"10.1155","volume":"2018","author":[{"given":"Lu","family":"Ren","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2539-1135","authenticated-orcid":true,"given":"Min","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0336-952X","authenticated-orcid":true,"given":"Lanlan","family":"Geng","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peiyu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6899-0616","authenticated-orcid":true,"given":"Sitang","family":"Gong","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, Guangzhou 510623, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2490-4798","authenticated-orcid":true,"given":"Ding-You","family":"Li","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Children\u2019s Mercy Kansas City, University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2013.1629"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2016.09.018"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.yapd.2015.04.005"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1007\/BF00540253"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1136\/adc.65.9.936"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.4292\/wjgpt.v3.i3.29"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-10-31"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2015.03.001"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2010.0827"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1997.tb09020.x"}],"container-title":["Gastroenterology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2018\/3097468.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2018\/3097468.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/grp\/2018\/3097468.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,4]],"date-time":"2018-03-04T18:31:05Z","timestamp":1520188265000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/grp\/2018\/3097468\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":10,"alternative-id":["3097468","3097468"],"URL":"https:\/\/doi.org\/10.1155\/2018\/3097468","relation":{},"ISSN":["1687-6121","1687-630X"],"issn-type":[{"type":"print","value":"1687-6121"},{"type":"electronic","value":"1687-630X"}],"subject":[],"published":{"date-parts":[[2018]]}}}