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As such, it lends itself to being a drug of abuse, particularly in the adolescent population. This retrospective study evaluated carbamazepine abuse, treatment course, and associated morbidity in Chinese adolescents. The median dose of carbamazepine resulting in overdose was 2,000\u2009mg (800\u20135,000). Patients were largely from urban-rural fringe areas (76.47%, 52.94%) with school performance within the last 1\/3 range and (52.94%) unsupervised by parents. 35.29% experienced an obvious sense of euphoria. All patients had nervous system symptoms, 6 (35.29%) cases developed coma (GCS &lt; 8), and 5 (29.41%) cases experienced convulsion. Four cases were treated with hemodialysis. The incidence rate in young patients with repeat carbamazepine use and without the supervision of parents was higher than that in first-time users (5\/7 versus 4\/10), but the difference was not significant. The toxic dose of repeat users was 3428 \u00b1 1035\u2009mg, significantly higher than that of 1470 \u00b1 646\u2009mg in first-time users (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.001<\/mml:mn><\/mml:math>). Carbamazepine can produce a sense of euphoria, which is more likely to lead to its abuse and overdose in adolescents. To prevent carbamazepine abuse and overdose will be critical in educating at-risk adolescents and preventing associated morbidities in the future.<\/jats:p>","DOI":"10.1155\/2018\/3201203","type":"journal-article","created":{"date-parts":[[2018,3,22]],"date-time":"2018-03-22T19:31:06Z","timestamp":1521747066000},"page":"1-6","source":"Crossref","is-referenced-by-count":12,"title":["A Clinical Study of Toxication Caused by Carbamazepine Abuse in Adolescents"],"prefix":"10.1155","volume":"2018","author":[{"given":"Wei","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Lin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, 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