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Data mining (DM) is the key technique for the discovery of the useful information from massive datasets. In our work, we take advantage of both platforms to design a real-time and intelligent mobile health-care system for chronic disease detection based on IoT device data, government-provided public data and user input data. The purpose of our work is the provision of a practical assistant system for self-based patient health care, as well as the design of a complementary system for patient disease diagnosis. This system was only applied to hypertensive disease during the first research stage. Nevertheless, a detailed design, an implementation, a clear overview of the whole system, and a significant guide for further work are provided; the entire step-by-step procedure is depicted. 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