{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T11:06:20Z","timestamp":1793012780819,"version":"4.5.0"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81400374"],"award-info":[{"award-number":["81400374"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2018KY543"],"award-info":[{"award-number":["2018KY543"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2017KY113"],"award-info":[{"award-number":["2017KY113"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["Y20150265"],"award-info":[{"award-number":["Y20150265"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Zhejiang Medical Science and Technology Program","award":["81400374"],"award-info":[{"award-number":["81400374"]}]},{"name":"Zhejiang Medical Science and Technology Program","award":["2018KY543"],"award-info":[{"award-number":["2018KY543"]}]},{"name":"Zhejiang Medical Science and Technology Program","award":["2017KY113"],"award-info":[{"award-number":["2017KY113"]}]},{"name":"Zhejiang Medical Science and Technology Program","award":["Y20150265"],"award-info":[{"award-number":["Y20150265"]}]},{"name":"Zhejiang Medical Science and Technology Program","award":["81400374"],"award-info":[{"award-number":["81400374"]}]},{"name":"Zhejiang Medical Science and Technology Program","award":["2018KY543"],"award-info":[{"award-number":["2018KY543"]}]},{"name":"Zhejiang Medical Science and Technology Program","award":["2017KY113"],"award-info":[{"award-number":["2017KY113"]}]},{"name":"Zhejiang Medical Science and Technology Program","award":["Y20150265"],"award-info":[{"award-number":["Y20150265"]}]},{"name":"Wenzhou Science and Technology Program","award":["81400374"],"award-info":[{"award-number":["81400374"]}]},{"name":"Wenzhou Science and Technology Program","award":["2018KY543"],"award-info":[{"award-number":["2018KY543"]}]},{"name":"Wenzhou Science and Technology Program","award":["2017KY113"],"award-info":[{"award-number":["2017KY113"]}]},{"name":"Wenzhou Science and Technology Program","award":["Y20150265"],"award-info":[{"award-number":["Y20150265"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>\n                    <jats:italic>Purpose<\/jats:italic>\n                    . To determine conjunctival overlap over the edge of soft contact lens and to visualize the peripheral postlens tear film (PoLTF) underneath soft contact lenses using ultrahigh-resolution optical coherence tomography (UHR-OCT).\n                    <jats:italic>Methods<\/jats:italic>\n                    . Twenty participants (4 males and 16 females, 23.0\u2009\u00b1\u20093.7 years) were fitted with two different types of soft contact lenses randomly. The limbus with lens was imaged with the UHR-OCT at the horizontal meridian every two hours up to 6 hours during lens wear. The conjunctival overlap was ranked as the percentage of the edge covered by the conjunctiva. The frequency of occurrence for visualized peripheral PoLTF was determined.\n                    <jats:italic>Results<\/jats:italic>\n                    . The average conjunctival overlaps at insertion were 49% and 73% for galyfilcon A and balafilcon A lenses and increased significantly to 84% and 90% by 6 hours of lens wear (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                      <mml:mrow>\n                        <mml:mi>P<\/mml:mi>\n                        <mml:mo>&lt;<\/mml:mo>\n                        <mml:mn>0.001<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ). Lenses with rounded edges had more conjunctival overlap than the lenses with angled edges (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                      <mml:mrow>\n                        <mml:mi>P<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>0.014<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ). There were significant decreases for PoLTF on the conjunctiva (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                      <mml:mrow>\n                        <mml:mi>P<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>0.014<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ) and peripheral cornea (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                      <mml:mrow>\n                        <mml:mi>P<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>0.004<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ) over the study period compared to insertion. The percentage of subjects with PoLTF on the conjunctiva (32.5%) and peripheral cornea (36%) were greater in subjects wearing balafilcon A lenses (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                      <mml:mrow>\n                        <mml:mi>P<\/mml:mi>\n                        <mml:mo>=<\/mml:mo>\n                        <mml:mn>0.017<\/mml:mn>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ).\n                    <jats:italic>Conclusions<\/jats:italic>\n                    . Increased conjunctival overlap over the lens edges and reduced PoLTF underneath the peripheral region of soft contact lenses were shown during lens daily wear. The lens edge configuration may play a role in conjunctival response and peripheral PoLTF.\n                  <\/jats:p>","DOI":"10.1155\/2018\/3463595","type":"journal-article","created":{"date-parts":[[2018,5,13]],"date-time":"2018-05-13T19:31:05Z","timestamp":1526239865000},"page":"1-6","source":"Crossref","is-referenced-by-count":4,"title":["Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9408-4916","authenticated-orcid":true,"given":"Lele","family":"Cui","sequence":"first","affiliation":[{"name":"Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sisi","family":"Chen","sequence":"additional","affiliation":[{"name":"Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, 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