{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:53:46Z","timestamp":1753887226149,"version":"3.41.2"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,9,26]],"date-time":"2018-09-26T00:00:00Z","timestamp":1537920000000},"content-version":"vor","delay-in-days":268,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31600852","81473749","81771202"],"award-info":[{"award-number":["31600852","81473749","81771202"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["15411969600"],"award-info":[{"award-number":["15411969600"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:p><jats:italic>Objective.<\/jats:italic> We aimed to investigate the effectiveness of acupoint polyglactin 910 (PGLA) embedding in patients with cervical spondylotic radiculopathy (CSR). <jats:italic>Methods.<\/jats:italic> A total of 102 CSR patients with neck and shoulder pain were recruited and assigned randomly into three groups: the sham acupoint embedding (SAE) group, the middle\u2010layer acupoint PGLA embedding (MAPE) group, and the deep\u2010layer acupoint PGLA embedding (DAPE) group. The primary outcomes were Visual Analog Scale (VAS) scores showing the analgesic effects of treatment. Secondary outcomes included clinical symptoms (evaluated by the Yasuhisa Tanaka 20 (YT\u201020) score and the neck disability index (NDI)) and patient health status (evaluated by the 36\u2010item short\u2010form survey (SF\u201036)) as reported in the trial. <jats:italic>Results.<\/jats:italic> Compared with the SAE group, VAS scores were significantly reduced at 1, 2, 3, 4, and 10 weeks after the first treatment in both the DAPE and MAPE groups (<jats:italic>P<\/jats:italic> &lt; 0.001). Moreover, there were statistically significant increases in the weekly YT\u201020 scores and significant reductions of the weekly NDI scores compared with baseline values in both the DAPE and MAPE groups (<jats:italic>P<\/jats:italic> &lt; 0.001). Compared with baseline values, both the physical component summary (PCS) and the mental component summary scores of the SF\u201036 at 2, 3, 4, and 10 weeks were significantly higher in the DAPE and MAPE groups (<jats:italic>P<\/jats:italic> &lt; 0.001). There were significant lower VAS scores (<jats:italic>P<\/jats:italic> &lt; 0.01), higher PCS scores (<jats:italic>P<\/jats:italic> &lt; 0.05) at 3 weeks, and lower NDI scores (<jats:italic>P<\/jats:italic> &lt; 0.05) at 4 weeks in the DAPE group compared with the MAPE group. <jats:italic>Conclusions.<\/jats:italic> Both DAPE and MAPE showed significant and long\u2010lasting effects on alleviating pain and improving clinical symptoms as well as quality of life in CSR patients with neck and shoulder pain. A more intense effect was seen in the DAPE group compared with the MAPE group.<\/jats:p>","DOI":"10.1155\/2018\/3465897","type":"journal-article","created":{"date-parts":[[2018,9,26]],"date-time":"2018-09-26T23:34:59Z","timestamp":1538004899000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Acupoint Embedding of Polyglactin 910 Sutures in Patients with Chronic Pain due to Cervical Spondylotic Radiculopathy: A Multicenter, Randomized, Controlled Clinical Trial"],"prefix":"10.1155","volume":"2018","author":[{"given":"Yu-Xia","family":"Chu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Qiang","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan-Yuan","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan-Hua","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Si-Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong-Bo","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3191-1179","authenticated-orcid":false,"given":"Yan-Qing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0163-3865","authenticated-orcid":false,"given":"Wen-Shan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,26]]},"reference":[{"key":"e_1_2_12_1_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11420-011-9218-z"},{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/BSD.0b013e31820d77ea"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2008.2598"},{"volume-title":"Classification of Chronic Pain","year":"1994","author":"Merskey H.","key":"e_1_2_12_4_2"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-15-129"},{"key":"e_1_2_12_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmr.2011.02.013"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pop.2013.08.004"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/acupmed-2013-010317"},{"key":"e_1_2_12_9_2","first-page":"931","article-title":"Preliminary study on depth of embedded catgut and qi arrival at cervical Jiaji (EX-B 2) under ultrasound guidance","volume":"35","author":"Sun W.","year":"2015","journal-title":"Chinese Acupuncture & Moxibustion"},{"key":"e_1_2_12_10_2","first-page":"1001","article-title":"Effective anatomic structures of ultrasound-guide acupoint embedding therapy for cervical spondylosis","volume":"35","author":"Sun W.","year":"2015","journal-title":"Chinese Acupuncture & Moxibustion"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000001857"},{"key":"e_1_2_12_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.math.2012.11.005"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/acupmed.2011.010084"},{"key":"e_1_2_12_14_2","first-page":"1","article-title":"A biologic comparison of polyglactin 910 and polyglycolic acid synthetic absorbable sutures","volume":"141","author":"Craig P. 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