{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:48:59Z","timestamp":1787017739448,"version":"build-2736575974"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T00:00:00Z","timestamp":1536796800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2018,9,13]]},"abstract":"<jats:p>Hepatitis A is a common viral infection with a benign course but in rare cases can progress to acute liver failure. It usually presents with abdominal pain, nausea, vomiting, diarrhea, jaundice, anorexia, or asymptomatically, but it can also present atypically with relapsing hepatitis and prolonged cholestasis. In addition, extrahepatic manifestations have been reported, including urticarial and maculopapular rash, acute kidney injury, autoimmune hemolytic anemia, aplastic anemia, acute pancreatitis, mononeuritis, reactive arthritis, glomerulonephritis, cryoglobulinemia, Guillain\u2013Barre syndrome, and pleural or pericardial effusion. A rare manifestation of hepatitis A is acute myocarditis. We report a case of a young woman who presented with \u201cflu-like symptoms\u201d and was found to have severe elevation of liver enzymes due to acute hepatitis A infection. On her 3rd day of admission, the patient developed chest pain and nonspecific electrocardiographic changes. Her troponins rose to 16.4 \u2009ng\/mL, and a transthoracic echocardiogram revealed global hypokinesis and a depressed ejection fraction at 30%. A CT angiography showed no evidence of significant coronary artery disease. The patient was managed supportively, and symptoms and laboratory findings slowly improved over the next 7 days. Her chest pain resolved and a follow-up echocardiogram showed improved ejection fraction to 45%.<\/jats:p>","DOI":"10.1155\/2018\/3625139","type":"journal-article","created":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T19:31:54Z","timestamp":1536867114000},"page":"1-6","source":"Crossref","is-referenced-by-count":22,"title":["A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis\u2014A Case Report with Literature Review"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8017-6406","authenticated-orcid":true,"given":"Olivia","family":"Allen","sequence":"first","affiliation":[{"name":"Internal Medicine Department, Beaumont Hospital, Royal Oak, MI, USA"},{"name":"Oakland University William Beaumont School of Medicine, Rochester, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Edhi","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Beaumont Hospital, Royal Oak, MI, USA"},{"name":"Oakland University William Beaumont School of Medicine, Rochester, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8951-5796","authenticated-orcid":true,"given":"Adam","family":"Hafeez","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Beaumont Hospital, Royal Oak, MI, USA"},{"name":"Oakland University William Beaumont School of Medicine, Rochester, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1805-992X","authenticated-orcid":true,"given":"Alexandra","family":"Halalau","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Beaumont Hospital, Royal Oak, MI, USA"},{"name":"Oakland University William Beaumont School of Medicine, Rochester, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2013.10.023"},{"issue":"11","key":"2","first-page":"1027","volume":"86","year":"2012","journal-title":"American Family Physician"},{"key":"3","year":"2018"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1159\/000252779"},{"issue":"4","key":"5","first-page":"192","volume":"1","year":"2010","journal-title":"Annals of Hepatology"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2011.02.017"},{"key":"7","first-page":"391","volume":"56","year":"2008","journal-title":"Journal of the Association of Physicians of India"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12842"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.5543\/tkda.2015.47750"},{"issue":"3","key":"10","first-page":"180","volume":"15","year":"2013","journal-title":"Israel Medical Association Journal"},{"key":"11","year":"2012"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(11)60648-x"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.95.1.163"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/171.supplement_1.s15"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.93.5.841"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.107.186093"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1996.tb00737.x"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1136\/heart.85.5.499"},{"issue":"4","key":"19","first-page":"431","volume":"150","year":"1989","journal-title":"Western Journal of Medicine"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2018\/3625139.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2018\/3625139.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2018\/3625139.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T19:31:57Z","timestamp":1536867117000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crim\/2018\/3625139\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,13]]},"references-count":19,"alternative-id":["3625139","3625139"],"URL":"https:\/\/doi.org\/10.1155\/2018\/3625139","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,13]]}}}