{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T16:33:57Z","timestamp":1740155637088,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>Spinal muscular atrophy is a genetic neuromuscular disease characterised by muscle atrophy, hypotonia, weakness, and progressive paralysis. Usually, these patients display increased fat mass deposition and reductions in fat-free mass and resting energy expenditure\u2014an unfavourable condition that facilitates the development of obesity. However, weight management of these patients remains poorly described. Hence, the aim of this case report was to describe the clinical presentation and weight management of a 31-year-old male patient with spinal muscular atrophy type III, class I obesity, and metabolic syndrome treated for 1 year by means of a personalised multistep cognitive-behavioural treatment for obesity. The treatment produced a weight loss of 7.2\u2009kg (7.1%), which was associated with a marked improvement in both the patient\u2019s self-reported general conditions and obesity-related cardiometabolic profile, and no adverse effects in terms of spinal muscular atrophy (i.e., reductions in fat-free mass or resting energy expenditure).<\/jats:p>","DOI":"10.1155\/2018\/4058429","type":"journal-article","created":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T19:31:27Z","timestamp":1526585487000},"page":"1-4","source":"Crossref","is-referenced-by-count":3,"title":["Weight-Loss Cognitive-Behavioural Treatment and Essential Amino Acid Supplementation in a Patient with Spinal Muscular Atrophy and Obesity"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4277-4752","authenticated-orcid":true,"given":"Marwan","family":"El Ghoch","sequence":"first","affiliation":[{"name":"Department of Eating and Weight Disorders, Villa Garda Hospital, Garda, Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola Vittoria","family":"Bazzani","sequence":"additional","affiliation":[{"name":"Department of Radiology, Villa Garda Hospital, Garda, Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4028-1877","authenticated-orcid":true,"given":"Simona","family":"Calugi","sequence":"additional","affiliation":[{"name":"Department of Eating and Weight Disorders, Villa Garda Hospital, Garda, Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9796-3721","authenticated-orcid":true,"given":"Riccardo","family":"Dalle Grave","sequence":"additional","affiliation":[{"name":"Department of Eating and Weight Disorders, Villa Garda Hospital, Garda, Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2015.07.004"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(08)60921-6"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2016.10.020"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2009.03.009"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.2147\/dmso.s139496"},{"key":"6","first-page":"195","volume":"26","year":"2014","journal-title":"Annali Di Igiene"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s40519-015-0191-2"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/289645"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2015.01.017"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2010.5"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/133.1.261s"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.02.078"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1111\/febs.14081"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1097\/01.mco.0000172581.79266.19"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/s12349-010-0016-9"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.03.009"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2018\/4058429.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2018\/4058429.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2018\/4058429.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T19:31:28Z","timestamp":1526585488000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crim\/2018\/4058429\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":16,"alternative-id":["4058429","4058429"],"URL":"https:\/\/doi.org\/10.1155\/2018\/4058429","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"type":"print","value":"1687-9627"},{"type":"electronic","value":"1687-9635"}],"subject":[],"published":{"date-parts":[[2018]]}}}