{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T05:51:25Z","timestamp":1750830685033,"version":"3.37.3"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,9,3]],"date-time":"2018-09-03T00:00:00Z","timestamp":1535932800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2018,9,3]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To characterize and evaluate the MR imaging features of early myositis ossificans (MO) without calcification or ossification.<jats:italic> Methods<\/jats:italic>. The MRI manifestations of seven patients with pathologically proven early MO were retrospectively analyzed with regard to tumor location, size, margins, signal intensity, and enhancement appearance in MR images. Additionally, the surrounding soft-tissue edema and adjacent bone change were assessed.<jats:italic> Results<\/jats:italic>. All cases (n=7) had intramuscular tumor-like masses without calcifications. The lesions appeared as isointense in T1-weighted images (T1-WI) and inhomogeneous hyperintense in T2-weighted MR images (T2-WI). On T2-WI and postcontrast T1-WI, the heterogeneously high signal intensity in the expanded muscle interspersed with a few hypointense linear structures consistent with intact muscle fibers showed \u201cstriate pattern\u201d in the plane parallel with muscle fibers. The relatively hypointense areas with geometrical pattern consistent with the bundles of intact muscle fibers are found within the lesion with diffuse high signal intensity, displaying the \u201ccheckerboard-like pattern\u201d in the plane vertical to muscle fibers. A \u201cstriate pattern\u201d (n = 7) and \u201ccheckerboard-like pattern\u201d (n = 3) in the lesion appeared in T2-WI. In contrast-enhanced MRI images, all cases showed diffuse \u201cstriate pattern\u201d enhancement. Among them, one case demonstrated \u201ccheckerboard-like pattern\u201d enhancement. All cases had diffuse and prominent muscle edema that preserved the muscle fascicles. For two lesions located in the deep muscle group, the adjacent bone showed bone marrow edema.<jats:italic> Conclusion<\/jats:italic>. MR imaging has unique advantages for diagnosis of early MO without calcification or ossification: the \u201cstriate pattern\u201d and \u201ccheckerboard-like pattern\u201d appearance shown in T2-WI and contrast-enhanced MRI images can be helpful for differential diagnosis. MRI can delineate the extent of the tumor and provides accurate anatomical information, which is important in diagnosis, treatment, and follow-up.<\/jats:p>","DOI":"10.1155\/2018\/4186324","type":"journal-article","created":{"date-parts":[[2018,9,3]],"date-time":"2018-09-03T19:31:44Z","timestamp":1536003104000},"page":"1-6","source":"Crossref","is-referenced-by-count":8,"title":["MRI Findings of Early Myositis Ossificans without Calcification or Ossification"],"prefix":"10.1155","volume":"2018","author":[{"given":"Hexiang","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Radiology, The Affiliated Hospital of Qingdao University Qingdao, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei","family":"Nie","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Affiliated Hospital of Qingdao University Qingdao, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Qingdao Women and Children Hospital Qingdao, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Pathology, The Affiliated Hospital of Qingdao University Qingdao, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Affiliated Hospital of Qingdao University Qingdao, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonghua","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Puyang City Oilfield General Hospital, Puyang, Henan, 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