{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:14:19Z","timestamp":1740165259118,"version":"3.37.3"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Otolaryngology"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>Hunter syndrome is a lysosomal disease characterized by deficiency of the lysosomal enzyme iduronate-2-sulfatase (I2S). It has an estimated incidence of approximately 1 in 1,62,000 live male births. We report a case of Hunter syndrome diagnosed by an otorhinolaryngologist. To our knowledge, this is the first study diagnosed by an otorhinolaryngologist despite the fact that otorhinolaryngological symptoms manifest at a young age in this disease. The patient was a 4-year-old boy. He underwent adenotonsillectomy. Intubation was difficult, and he had some symptoms which are reasonable as a mucopolysaccharidosis. The otorhinolaryngologist should play an integral role in the multidisciplinary approach to the diagnosis and management of many children with MPS (mucopolysaccharidoses) disorders.<\/jats:p>","DOI":"10.1155\/2018\/4252696","type":"journal-article","created":{"date-parts":[[2018,5,13]],"date-time":"2018-05-13T19:31:21Z","timestamp":1526239881000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Hunter Syndrome Diagnosed by Otorhinolaryngologist"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6623-8546","authenticated-orcid":true,"given":"Ayako","family":"Hashimoto","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Shizuoka Children\u2019s Hospital, Shizuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadayuki","family":"Kumagai","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Fujieda City General Hospital, Fujieda, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Mineta","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.281.3.249"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2006.05.021"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-012-1703-y"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-014-9686-7"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2015.05.007"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/gim.0b013e31817701e6"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-013-1967-x"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.03.021"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgmr.2015.03.011"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-011-9378-5"}],"container-title":["Case Reports in Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2018\/4252696.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2018\/4252696.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2018\/4252696.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,5,13]],"date-time":"2018-05-13T19:31:23Z","timestamp":1526239883000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criot\/2018\/4252696\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":10,"alternative-id":["4252696","4252696"],"URL":"https:\/\/doi.org\/10.1155\/2018\/4252696","relation":{},"ISSN":["2090-6765","2090-6773"],"issn-type":[{"type":"print","value":"2090-6765"},{"type":"electronic","value":"2090-6773"}],"subject":[],"published":{"date-parts":[[2018]]}}}