{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T14:45:58Z","timestamp":1772808358162,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,8,2]],"date-time":"2018-08-02T00:00:00Z","timestamp":1533168000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2018,8,2]]},"abstract":"<jats:p>A composite lymphoma is the rare simultaneous occurrence of two or more distinct lymphomas within a single tissue or organ. Herein, we describe a case of a 51-year-old man presenting with a history of lower limb rash, fatigue, and bulky abdominopelvic lymphadenopathy. An excisional left iliac lymph node biopsy was notable for the composite presence of two distinct lymphoid neoplasms, nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL), and follicular lymphoma (FL). Multiplex PCR and FISH analyses failed to demonstrate a t(14;18)(q32;q21) translocation in either composite lymphoma component. A clonal light-chain kappa (V\/JC intron-kde) gene rearrangement was detected in the FL component only.<\/jats:p>","DOI":"10.1155\/2018\/4312594","type":"journal-article","created":{"date-parts":[[2018,8,2]],"date-time":"2018-08-02T19:33:39Z","timestamp":1533238419000},"page":"1-4","source":"Crossref","is-referenced-by-count":3,"title":["Composite t(14;18)-Negative Follicular Lymphoma and Nodular Lymphocyte-Predominant Hodgkin Lymphoma"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6110-8232","authenticated-orcid":true,"given":"John Patrick","family":"O\u2019Neill","sequence":"first","affiliation":[{"name":"St. James\u2019s Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona","family":"Quinn","sequence":"additional","affiliation":[{"name":"St. James\u2019s Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Dowling","sequence":"additional","affiliation":[{"name":"St. James\u2019s Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Walker","sequence":"additional","affiliation":[{"name":"St. James\u2019s Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Triona","family":"Hayes","sequence":"additional","affiliation":[{"name":"Bons Secours Hospital, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Bird","sequence":"additional","affiliation":[{"name":"Bons Secours Hospital, Cork, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Flavin","sequence":"additional","affiliation":[{"name":"St. James\u2019s Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"2","doi-asserted-by":"publisher","DOI":"10.1043\/0003-9985(2000)124<1376:AUVOCL>2.0.CO;2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1200\/jco.1999.17.12.3804"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200405000-00018"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200312000-00012"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1080\/10428190310001643421"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0000000000000140"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0b013e318165b0d6"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403202"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199904223401604"},{"issue":"5","key":"11","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF03402211","volume":"7","year":"2001","journal-title":"Molecular Medicine"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyv101"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/s1470-2045(14)70153-6"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1309\/ky8c-lcyn-qhj6-4c6r"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1056\/nejm200010123431514"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0b013e3182147f91"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2012.11.018"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2003.011882"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-005-0008-1"}],"container-title":["Case Reports in Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2018\/4312594.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2018\/4312594.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2018\/4312594.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T15:35:38Z","timestamp":1571672138000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crihem\/2018\/4312594\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,2]]},"references-count":18,"alternative-id":["4312594","4312594"],"URL":"https:\/\/doi.org\/10.1155\/2018\/4312594","relation":{},"ISSN":["2090-6560","2090-6579"],"issn-type":[{"value":"2090-6560","type":"print"},{"value":"2090-6579","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,2]]}}}