{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T22:32:18Z","timestamp":1783636338608,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T00:00:00Z","timestamp":1527724800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007835","name":"Silesian University of Technology","doi-asserted-by":"crossref","award":["BK-204\/RAU1\/2017\/9"],"award-info":[{"award-number":["BK-204\/RAU1\/2017\/9"]}],"id":[{"id":"10.13039\/501100007835","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Diabetes Research"],"published-print":{"date-parts":[[2018,5,31]]},"abstract":"<jats:p><jats:italic>Aim<\/jats:italic>. The aim of the study was to assess markers of anemia in type 1 diabetes (T1D) children, compare them to results obtained in the control group, and estimate their relation to BMI SDS. <jats:italic>Methods<\/jats:italic>. 94 (59% \u2640) T1D children without other autoimmune disorders, aged 12.5\u2009\u00b1\u20094.1 years, T1D duration: 4.2\u2009\u00b1\u20093.6 years, HbA1c 7.3\u2009\u00b1\u20091.5% (57\u2009\u00b1\u200912.6\u2009mmol\/mol). Sex- and age-matched controls (43 children). In all children, anthropometric measurements, the blood count, iron turnover parameters, and vitamin B12 concentration were taken. <jats:italic>Results<\/jats:italic>. T1DM children had significantly higher red cell distribution width (RDW) (13.6 versus 12.6%; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>), hepcidin (0.25 versus 0.12\u2009ng\/ml; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>), and vitamin B12 concentrations (459 versus 397\u2009pg\/ml; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:math>) and lower TIBC (59.09 versus 68.15\u2009<jats:italic>\u03bc<\/jats:italic>mol\/l; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>) than in the control group. Logistic regression revealed that RDW, TIBC (both <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>), and hepcidin (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>) significantly differentiated both groups. In T1DM children, BMI SDS negatively correlated with vitamin B12 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:math>) concentration and mean corpuscular hemoglobin concentration (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>) and positively with TIBC (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:math>) and HbA1c (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>). <jats:italic>Conclusions<\/jats:italic>. Patients and controls differed especially in terms of RDW and TIBC. In studied T1DM children, BMI SDS was associated to iron metabolism parameters and vitamin B12 concentration.<\/jats:p>","DOI":"10.1155\/2018\/5184354","type":"journal-article","created":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T19:37:42Z","timestamp":1527795462000},"page":"1-7","source":"Crossref","is-referenced-by-count":11,"title":["Markers of Anemia in Children with Type 1 Diabetes"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4422-7704","authenticated-orcid":true,"given":"Ewa","family":"Rusak","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Children\u2019s Diabetology, Medical University of Silesia, 40-752 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Rotarska-Mizera","sequence":"additional","affiliation":[{"name":"Data Mining Division, Faculty of Automatic Control, Electronics, and Computer Science, Silesian University of Technology, 44-100 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Adamczyk","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, 40-752 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogdan","family":"Mazur","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, 40-752 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8004-9864","authenticated-orcid":true,"given":"Joanna","family":"Polanska","sequence":"additional","affiliation":[{"name":"Data Mining Division, Faculty of Automatic Control, Electronics, and Computer Science, Silesian University of Technology, 44-100 Gliwice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agata","family":"Chobot","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Hepatology, Clinical Hospital No. 1, 41-800 Zabrze, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2016.02.017"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60568-7"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2014.06.001"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.23750\/abm.v88i1.6049"},{"issue":"10b","key":"5","first-page":"26","volume":"27","year":"2014","journal-title":"Post\u0119py Nauk Medycznych"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1002\/1520-7560(200005\/06)16:3<172::AID-DMRR117>3.0.CO;2-D"},{"issue":"2","key":"7","first-page":"88","volume":"18","year":"2014","journal-title":"Iranian Biomedical 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