{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:20:14Z","timestamp":1773030014036,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Thyroid Research"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>. Different types of thyroiditis may share some parallel clinical and biochemical features. Timely intervention can significantly reduce morbidity and mortality.<jats:italic>Aim<\/jats:italic>. Aim of this study is to find the frequency of various thyroiditis, study the cytomorphological features and correlate with clinical findings including radiological findings, thyroid function test, and anti-thyroid peroxidase antibodies (Anti-TPO antibodies).<jats:italic>Materials and Methods<\/jats:italic>. The study included consecutive 110 cases of thyroiditis. Detailed cytomorphological features were studied and correlated with ultrasonography findings, thyroid function test, anti-thyroid peroxidase antibodies (anti-TPO) and histopathological features where thyroidectomy specimens were received for histopathological examination.<jats:italic>Results<\/jats:italic>. The majority were Hashimoto\u2019s thyroiditis (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">100<\/mml:mn><\/mml:math>) and females (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">103<\/mml:mn><\/mml:math>). Other forms of thyroiditis were Hashimoto\u2019s thyroiditis with colloid goiter (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">5<\/mml:mn><\/mml:math>), De Quervain\u2019s thyroiditis (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">3<\/mml:mn><\/mml:math>), and one case each of postpartum thyroiditis and Hashimoto\u2019s thyroiditis with associated malignancy. The majority of patients were in the age group of 21\u201340 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">70<\/mml:mn><\/mml:math>) and the majority (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">73<\/mml:mn><\/mml:math>) had diffuse enlargement of thyroid. The majority of patients were hypothyroid (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">52<\/mml:mn><\/mml:math>). The serum anti-TPO antibodies were elevated in 47 patients out of 71 patients. In the 48 patients who underwent ultrasonography, 38 were diagnosed as having thyroiditis. The most consistent cytomorphological features seen in fine-needle aspiration smears of Hashimoto\u2019s thyroiditis were increased background lymphocytes, lymphocytic infiltration of thyroid follicular cell clusters, and Hurthle cells.<jats:italic>Conclusion<\/jats:italic>. The diagnostic cytological features in Hashimoto\u2019s thyroiditis are increased background lymphocytes, lymphocytic infiltration of thyroid follicular cell clusters, and Hurthle cells. FNAC remains the \u201cGold Standard\u201d for diagnosing Hashimoto\u2019s thyroiditis. Clinical history, thyroid function, and biochemical parameters are the key for diagnosis of other forms of thyroiditis.<\/jats:p>","DOI":"10.1155\/2018\/5246516","type":"journal-article","created":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T23:33:14Z","timestamp":1519947194000},"page":"1-7","source":"Crossref","is-referenced-by-count":17,"title":["Cytomorphological Spectrum of Thyroiditis: A Review of 110 Cases"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7854-4564","authenticated-orcid":true,"given":"Shirish S.","family":"Chandanwale","sequence":"first","affiliation":[{"name":"Department of Pathology, Dr. D. Y. Patil Medical College, Pimpri, Pune 411018, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Nair","sequence":"additional","affiliation":[{"name":"Dr. D. Y. 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