{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T08:13:51Z","timestamp":1767168831638,"version":"build-2238731810"},"reference-count":48,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,31]],"date-time":"2018-01-31T00:00:00Z","timestamp":1517356800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007771","name":"\u015al\u0105ski Uniwersytet Medyczny","doi-asserted-by":"publisher","award":["KNW 1 103\/P\/2\/0"],"award-info":[{"award-number":["KNW 1 103\/P\/2\/0"]}],"id":[{"id":"10.13039\/100007771","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Disease Markers"],"published-print":{"date-parts":[[2018,1,31]]},"abstract":"<jats:p>\n                    25-hydroxyvitamin D (25(OH)D) plays a crucial role in human homeostasis. Its deficiency (vitamin D deficiency\u2014VDD), being common in European population, combined with elevated concentration of parathyroid hormone (PTH), represents a vicious cycle of mechanisms leading to heart failure (HF). Despite several papers published in that field, the effect of VDD and PTH concentration on cardiovascular system remains unequivocal; thus, the aim of the study was to compare these data among HF and non-HF patients being prospectively enrolled into the study during hospital stay in the cardiology ward. Patients with HF had higher PTH concentration (85.0\u2009\u00b1\u200952.6 versus 64.5\u2009\u00b1\u200931.7,\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                      <mml:mi>p<\/mml:mi>\n                      <mml:mo>=<\/mml:mo>\n                      <mml:mn>0.02<\/mml:mn>\n                    <\/mml:math>\n                    ) compared to non-HF patients. Mean PTH values were associated with the clinical status expressed by the New York Heart Association class (NYHA class) (\u201c0\u201d\u201466.04, \u201cI\u201d\u201456.57, \u201cII\u201d\u201472.30, \u201cIII\u201d\u201485.59, and \u201cIV\u201d\u2014144.37\u2009pg\/ml,\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                      <mml:mi>p<\/mml:mi>\n                      <mml:mo>=<\/mml:mo>\n                      <mml:mn>0.00004<\/mml:mn>\n                    <\/mml:math>\n                    ). Interestingly, neither 25(OH)D (31.5 versus 29.7\u2009ng\/ml,\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                      <mml:mi>p<\/mml:mi>\n                      <mml:mo>=<\/mml:mo>\n                      <mml:mi mathvariant=\"normal\">n<\/mml:mi>\n                      <mml:mi mathvariant=\"normal\">s<\/mml:mi>\n                    <\/mml:math>\n                    ) nor phosphorus (P) (1.23 versus 1.18\u2009mmol\/l,\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                      <mml:mi>p<\/mml:mi>\n                      <mml:mo>=<\/mml:mo>\n                      <mml:mi mathvariant=\"normal\">n<\/mml:mi>\n                      <mml:mi mathvariant=\"normal\">s<\/mml:mi>\n                    <\/mml:math>\n                    ) nor total calcium (Ca\n                    <jats:sup>2+<\/jats:sup>\n                    ) concentration (2.33 versus 2.37\u2009mmol\/l,\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\">\n                      <mml:mi>p<\/mml:mi>\n                      <mml:mo>=<\/mml:mo>\n                      <mml:mi mathvariant=\"normal\">n<\/mml:mi>\n                      <mml:mi mathvariant=\"normal\">s<\/mml:mi>\n                    <\/mml:math>\n                    ) differed among the groups. Reassuming PTH serum concentration in contrary to 25(OH)D, P and Ca\n                    <jats:sup>2+<\/jats:sup>\n                    are significantly raised among the patients with HF and shows significant relationship with the clinical status expressed by the NYHA class.\n                  <\/jats:p>","DOI":"10.1155\/2018\/5287573","type":"journal-article","created":{"date-parts":[[2018,1,31]],"date-time":"2018-01-31T18:34:04Z","timestamp":1517423644000},"page":"1-9","source":"Crossref","is-referenced-by-count":4,"title":["The Role of Parathyroid Hormone and Vitamin D Serum Concentrations in Patients with Cardiovascular Diseases"],"prefix":"10.1155","volume":"2018","author":[{"given":"Agnieszka","family":"Kolaszko","sequence":"first","affiliation":[{"name":"2nd Department of Cardiology, Medical Faculty, Medical University of Silesia, Katowice 10 M. Sk\u0142odowskiej-Curie Street, 41-800 Zabrze, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewa","family":"Nowalany-Kozielska","sequence":"additional","affiliation":[{"name":"2nd Department of Cardiology, Medical Faculty, Medical University of Silesia, Katowice 10 M. Sk\u0142odowskiej-Curie Street, 41-800 Zabrze, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3478-0108","authenticated-orcid":true,"given":"Piotr","family":"Ceranowicz","sequence":"additional","affiliation":[{"name":"Department of Physiology, Medical Faculty, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Krakow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0187-1364","authenticated-orcid":true,"given":"Beata","family":"Morawiec","sequence":"additional","affiliation":[{"name":"2nd Department of Cardiology, Medical Faculty, Medical University of Silesia, Katowice 10 M. Sk\u0142odowskiej-Curie Street, 41-800 Zabrze, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6274-5831","authenticated-orcid":true,"given":"Grzegorz","family":"Kubiak","sequence":"additional","affiliation":[{"name":"2nd Department of Cardiology, Medical Faculty, Medical University of Silesia, Katowice 10 M. 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