{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:24:31Z","timestamp":1792157071825,"version":"4.4.0"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,7,31]],"date-time":"2018-07-31T00:00:00Z","timestamp":1532995200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["459228\/2014-5)"],"award-info":[{"award-number":["459228\/2014-5)"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["459228\/2014-5)"],"award-info":[{"award-number":["459228\/2014-5)"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","award":["459228\/2014-5)"],"award-info":[{"award-number":["459228\/2014-5)"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Research and Management"],"published-print":{"date-parts":[[2018,7,31]]},"abstract":"<jats:p>Viscosupplementation is a minimally invasive technique that replaces synovial fluid by intra-articular injection of hyaluronic acid (HA). Although effective in some joints, there is not conclusive evidence regarding temporomandibular disorders. This case series described the efficacy of a viscosupplementation protocol in intra-articular temporomandibular disorders. Ten patients with a diagnosis of disc displacement and\/or osteoarthritis by Research Diagnostic Criteria for Temporomandibular Disorders (RDC\/TMD) were submitted to four monthly injections of low or medium molecular weight HA. Pain, mandibular function, image analysis by tomography and magnetic resonance, and quality of life were assessed at baseline and follow-ups (1 and 6 months). Pain, jaw range-of-motion, mandibular function, and quality of life improved at follow-up evaluations. Osteoarthritis changes decreased, and 20% of patients improved mandibular head excursion after treatment. Resolution of effusion and improvement in disc morphology were observed for most patients. This viscosupplementation protocol reduced pain and symptoms associated with internal derangement of temporomandibular joint, improved quality of life, and showed benefits from both low and medium molecular weight HA in alternate cycles.<\/jats:p>","DOI":"10.1155\/2018\/5392538","type":"journal-article","created":{"date-parts":[[2018,7,31]],"date-time":"2018-07-31T19:44:07Z","timestamp":1533066247000},"page":"1-9","source":"Crossref","is-referenced-by-count":24,"title":["Effectiveness of Sequential Viscosupplementation in Temporomandibular Joint Internal Derangements and Symptomatology: A Case Series"],"prefix":"10.1155","volume":"2018","author":[{"given":"Roberta Maria Drumond Furtado Bossi","family":"Fonseca","sequence":"first","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Patologia, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Januzzi","sequence":"additional","affiliation":[{"name":"Faculdade Ciodonto, Sete Lagoas, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7965-6787","authenticated-orcid":true,"given":"Luciano Ambrosio","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Departamento de Radiologia, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil"},{"name":"9 Hospital Maternidade Therezinha de Jesus-HMTJ\/JF, Suprema-Faculdade de Ci\u00eancias M\u00e9dicas e da Sa\u00fade, Juiz de Fora, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Grossmann","sequence":"additional","affiliation":[{"name":"Departamento de Ci\u00eancias Morfol\u00f3gicas, Instituto de Ci\u00eancias B\u00e1sicas da Sa\u00fade, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2447-7607","authenticated-orcid":true,"given":"Antonio Carlos Pires","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Departamento de Radiologia, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Gon\u00e7alves de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Faculdade de Farm\u00e1cia, Universidade Anhembi Morumbi, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4147-5614","authenticated-orcid":true,"given":"\u00c9rica Leandro Marciano","family":"Vieira","sequence":"additional","affiliation":[{"name":"Departamento de Cl\u00ednica M\u00e9dica, Faculdade de Medicina, UFMG, Belo Horizonte, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9621-5422","authenticated-orcid":true,"given":"Ant\u00f4nio L\u00facio","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Departamento de Cl\u00ednica M\u00e9dica, Faculdade de Medicina, UFMG, Belo Horizonte, MG, Brazil"},{"name":"Department of Psychiatry and Behavioral Sciences, The University of Texas, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2694-8521","authenticated-orcid":true,"given":"Camila Megale","family":"Almeida-Leite","sequence":"additional","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Patologia, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil"},{"name":"Departamento de Morfologia, Instituto de Ci\u00eancias Biol\u00f3gicas, UFMG, Belo Horizonte, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-3913(97)70145-8"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmra0802472"},{"key":"3","year":"2008"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.11607\/jop.1151"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2011.02228.x"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2005.01505.x"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.3928\/01477447-20100826-11"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-006-0260-1"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2000.105518"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/s0901-5027(97)81145-9"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1053\/sarh.2002.33720"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2009.02048.x"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-012-0940-0"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2006.04.001"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1186\/ar2774"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1038\/ncprheum0508"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2014.06.014"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2016.06.004"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2017.01.014"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.11607\/ofph.1783"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-013-0068-6"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.15.e644"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1179\/crn.2010.023"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12282"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2014.08.034"},{"issue":"4","key":"27","first-page":"301","volume":"6","year":"1992","journal-title":"Journal of Craniomandibular Disorders: Facial and Oral Pain"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/s0304-3959(01)00349-9"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(75)90044-5"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.2004.00193.x"},{"key":"31","first-page":"165","volume":"67","year":"1974","journal-title":"Svensk Tandlakare Tidskrift"},{"issue":"2","key":"32","first-page":"183","volume":"7","year":"1993","journal-title":"Journal of Orofacial Pain"},{"issue":"1","key":"33","first-page":"3","volume":"11","year":"1994","journal-title":"Community Dental Health"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.02.023"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.22.4.8181648"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1016\/j.coms.2014.09.007"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1172\/jci43766"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2009.03.715"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.2106\/jbjs.h.01573"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.4314\/ahs.v12i4.25"}],"container-title":["Pain Research and Management"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2018\/5392538.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2018\/5392538.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/prm\/2018\/5392538.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,7,31]],"date-time":"2018-07-31T19:44:09Z","timestamp":1533066249000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/prm\/2018\/5392538\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,31]]},"references-count":39,"alternative-id":["5392538","5392538"],"URL":"https:\/\/doi.org\/10.1155\/2018\/5392538","relation":{},"ISSN":["1203-6765","1918-1523"],"issn-type":[{"value":"1203-6765","type":"print"},{"value":"1918-1523","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,31]]}}}