{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:21:20Z","timestamp":1762474880735,"version":"build-2065373602"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,9,23]],"date-time":"2018-09-23T00:00:00Z","timestamp":1537660800000},"content-version":"vor","delay-in-days":265,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:p>\n                    Immune\u2010mediated central nervous system manifestations of group A\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2010hemolytic\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    (GABHS) infection include Sydenham\u2019s chorea, pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS)\u2014which includes tic and obsessive compulsive disorders\u2014and a variety of neurobehavioral disorders. We report a case of\n                    <jats:italic>Streptococcus dysgalactiae<\/jats:italic>\n                    subspecies\n                    <jats:italic>equisimilis<\/jats:italic>\n                    (group G\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    ) (GGS) infection associated with involuntary movements, complex tics, and emotional lability in an 11\u2010year\u2010old Japanese girl. Serum IgM and IgG antibodies to lysoganglioside were positive, and she responded rapidly to intravenous immunoglobulin treatment. Neuropsychiatric disorder associated with GGS infection was ultimately diagnosed. The present findings suggest that neuropsychiatric disorders can result from GGS infection and that the pathogenic mechanism is similar to that of GABHS infection. Future large\u2010scale studies should examine the relation between GGS infection and onset of neuropsychiatric disorder.\n                  <\/jats:p>","DOI":"10.1155\/2018\/6047318","type":"journal-article","created":{"date-parts":[[2018,9,23]],"date-time":"2018-09-23T19:30:59Z","timestamp":1537731059000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Neuropsychiatric Disorder Associated with Group G\n                    <i>Streptococcus<\/i>\n                    Infection"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7872-6563","authenticated-orcid":false,"given":"Rie","family":"Okumura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sawako","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsukasa","family":"Ohashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Magara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Tohyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8736-9027","authenticated-orcid":false,"given":"Hiroshi","family":"Sakuma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5545-0741","authenticated-orcid":false,"given":"Masaharu","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiko","family":"Saitoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,23]]},"reference":[{"key":"e_1_2_5_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2012.10.003"},{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.015644-0"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1311.061258"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(00)02765-3"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2006.06.017"},{"key":"e_1_2_5_6_2","first-page":"209","article-title":"Group C and G streptococci infections: emerging challenges","volume":"16","author":"Williams G. 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