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A 53-year-old male with metastatic pancreatic cancer presented to the hospital with acute-on-chronic respiratory failure approximately 24 hours after receiving a novel therapeutic combination. Chest imaging showed marked changes as concerning for pneumonitis. Infectious workup was negative. The patient had initial clinical improvement after receiving initial intravenous steroids and oxygen support but eventually deteriorated later opting for supportive measures only. With infection ruled out, drug-induced pneumonitis was felt to be the likely cause of the radiologic and clinical changes. The rapidity of onset of symptoms is the aspect being highlighted in this case.<\/jats:p>","DOI":"10.1155\/2018\/6314392","type":"journal-article","created":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T19:32:48Z","timestamp":1522611168000},"page":"1-5","source":"Crossref","is-referenced-by-count":2,"title":["An Extremely Rapid Case of Pneumonitis with the Use of Nivolumab for Pancreatic Adenocarcinoma"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3492-4397","authenticated-orcid":true,"given":"Rubens Barros","family":"Costa","sequence":"first","affiliation":[{"name":"Developmental Therapeutics Program, Feinberg School of Medicine and Robert H. Lurie Comprehensive Cancer Center of Northwestern University, 233 East Superior Street, Chicago, IL 60611, USA"},{"name":"Division of Hematology and Oncology, Robert H. 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