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However, few studies have reported the normal microbiota carriage in the URT of healthy Chinese children. In this study, we performed a 16S rDNA gene sequencing analysis of 83 anterior nares (ANs), 60 nasopharynx (NP), and 97 oropharynx (OP) samples from 98 healthy children in Shenzhen, China (\u226412 years of age). The microbiota in ANs and NP is the same at different ages and typical species in these sites include<jats:italic> Moraxella<\/jats:italic>,<jats:italic> Staphylococcus<\/jats:italic>,<jats:italic> Corynebacterium<\/jats:italic>,<jats:italic> Streptococcus<\/jats:italic>, and<jats:italic> Dolosigranulum<\/jats:italic>. By contrast, the OP is primarily colonized by<jats:italic> Streptococcus<\/jats:italic>,<jats:italic> Prevotella<\/jats:italic>,<jats:italic> Neisseria<\/jats:italic>,<jats:italic> Veillonella<\/jats:italic>,<jats:italic> Rothia<\/jats:italic>,<jats:italic> Leptotrichia<\/jats:italic>, and<jats:italic> Haemophilus<\/jats:italic>.<jats:italic> Streptococcus <\/jats:italic>and<jats:italic> Rothia <\/jats:italic>keep low abundance in OP microbiota of children<jats:bold> \u2264<\/jats:bold>1 year old, whereas<jats:italic> Prevotella<\/jats:italic>,<jats:italic> Neisseria<\/jats:italic>,<jats:italic> Haemophilus<\/jats:italic>, and<jats:italic> Leptotrichia<\/jats:italic> amass significantly in individuals<jats:bold> &gt;<\/jats:bold>1 year old. This work furnishes an important reference for understanding microbial dysbiosis in the URT of Chinese paediatric patients.<\/jats:p>","DOI":"10.1155\/2018\/6515670","type":"journal-article","created":{"date-parts":[[2018,6,14]],"date-time":"2018-06-14T23:33:16Z","timestamp":1529019196000},"page":"1-8","source":"Crossref","is-referenced-by-count":23,"title":["Microbiota Composition in Upper Respiratory Tracts of Healthy Children in Shenzhen, China, Differed with Respiratory Sites and Ages"],"prefix":"10.1155","volume":"2018","author":[{"given":"Heping","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Respiratory Diseases, Shenzhen Children\u2019s Hospital, Shenzhen 518026, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenkui","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Computer Science, City University of Hong Kong, Kowloon Tong 999077, Hong 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