{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:17:50Z","timestamp":1740165470571,"version":"3.37.3"},"reference-count":8,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,10,30]],"date-time":"2018-10-30T00:00:00Z","timestamp":1540857600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Anesthesiology"],"published-print":{"date-parts":[[2018,10,30]]},"abstract":"<jats:p>The purpose of this case report is to increase awareness that a diagnosis of malignant hyperthermia may have long-lasting or permanent effects on a patient\u2019s insurance eligibility or premiums despite legislation providing varying levels of protection from preexisting conditions or genetic discrimination. We present a case of severe rigors, unexplained severe metabolic acidosis, and severe hyperthermia in a patient after general anesthesia for extensive head and neck surgery. The patient was treated for malignant hyperthermia and demonstrated a significant clinical improvement with the administration of dantrolene. Even with an \u201calmost certain\u201d diagnosis of malignant hyperthermia by clinical presentation, genetic testing was negative and the gold-standard caffeine-halothane contracture test has yet to be performed. Laboratory results, clinical grading scales, and genetic testing support a diagnosis of malignant hyperthermia but the gold standard is a live muscle biopsy and caffeine-halothane contracture test. A clinical diagnosis of MH or a positive caffeine-halothane contracture test could result in exclusion from genetic discrimination legislature due to the fact that diagnosis can be confirmed without genetic testing. The fate of the Affordable Care Act may also affect how insurance companies scrutinize this disease. Improving accuracy of MH diagnosis in hospital discharge records will be crucial.<\/jats:p>","DOI":"10.1155\/2018\/6532821","type":"journal-article","created":{"date-parts":[[2018,10,30]],"date-time":"2018-10-30T19:31:15Z","timestamp":1540927875000},"page":"1-5","source":"Crossref","is-referenced-by-count":0,"title":["A Case Report of Suspected Malignant Hyperthermia: How Will the Diagnosis Affect a Patient\u2019s Insurability?"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3125-7808","authenticated-orcid":true,"given":"Brian M.","family":"Osman","sequence":"first","affiliation":[{"name":"University of Miami, Miller School of Medicine, Department of Anesthesiology, 1400 NW 12th Avenue, Suite 3075, Miami, FL 33136, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabela C.","family":"Saba","sequence":"additional","affiliation":[{"name":"University of Miami, Miller School of Medicine, Department of Anesthesiology, 1801 NW 9th Avenue, 5th Floor, Miami, FL 33136, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William A.","family":"Watson","sequence":"additional","affiliation":[{"name":"University of Miami, Miller School of Medicine, Department of Anesthesiology, 1611 NW 12th Avenue, Suite C-300, Miami, FL 33136, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"doi-asserted-by":"publisher","key":"1","DOI":"10.1186\/s13023-015-0310-1"},{"doi-asserted-by":"publisher","key":"3","DOI":"10.1097\/ALN.0000000000001877"},{"doi-asserted-by":"publisher","key":"4","DOI":"10.1097\/aln.0000000000000467"},{"doi-asserted-by":"publisher","key":"6","DOI":"10.1007\/s10551-017-3554-y"},{"doi-asserted-by":"publisher","key":"7","DOI":"10.1007\/s10897-014-9771-y"},{"issue":"1","key":"8","first-page":"355","volume":"10","year":"2014","journal-title":"Therapeutics and Clinical Risk Management"},{"doi-asserted-by":"publisher","key":"9","DOI":"10.1097\/00000542-199404000-00008"},{"doi-asserted-by":"publisher","key":"11","DOI":"10.1213\/ANE.0b013e31820b5f1f"}],"container-title":["Case Reports in Anesthesiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cria\/2018\/6532821.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cria\/2018\/6532821.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cria\/2018\/6532821.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,30]],"date-time":"2018-10-30T19:31:16Z","timestamp":1540927876000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cria\/2018\/6532821\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,30]]},"references-count":8,"alternative-id":["6532821","6532821"],"URL":"https:\/\/doi.org\/10.1155\/2018\/6532821","relation":{},"ISSN":["2090-6382","2090-6390"],"issn-type":[{"type":"print","value":"2090-6382"},{"type":"electronic","value":"2090-6390"}],"subject":[],"published":{"date-parts":[[2018,10,30]]}}}