{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:15:23Z","timestamp":1740165323980,"version":"3.37.3"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Rheumatology"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>Periodic fever with aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is an autoinflammatory disease manifested as recurrent febrile episodes associated with one of the following cardinal features: aphthous ulceration, pharyngitis, and cervical adenitis. It was initially described in children and thought to be a disease of pediatric age group. Few adult cases were also reported in the literature. We describe the case of a 39-year-old female affected by PFAPA who presented with a history of febrile episodes associated with aphthous ulceration, stomatitis, and tonsillitis for 4 years. The febrile episodes occurred at a regular interval of 4 weeks and resolved within 5 days. The patient underwent tonsillectomy without any significant improvement. The patient responded only to a single high dose of steroid during the attack. Although PFAPA was initially thought to be a disease of pediatric age group, it should be considered in patients with recurrent febrile illness in all age groups.<\/jats:p>","DOI":"10.1155\/2018\/6580835","type":"journal-article","created":{"date-parts":[[2018,5,2]],"date-time":"2018-05-02T19:38:29Z","timestamp":1525289909000},"page":"1-3","source":"Crossref","is-referenced-by-count":3,"title":["An Underlooked Cause of Periodic Fever (PFAPA) in an Adult Patient with No Response to Tonsillectomy"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0243-0202","authenticated-orcid":true,"given":"Fiaz","family":"Alam","sequence":"first","affiliation":[{"name":"Department of Medicine, Hamad General Hospital, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3313-2769","authenticated-orcid":true,"given":"Mohammed","family":"Hammoudeh","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hamad General Hospital, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-3476(87)80285-8"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-198909000-00026"},{"issue":"7","key":"3","volume":"59","year":"2012","journal-title":"Danish Medical Journal"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2009.01554.x"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/570418"},{"issue":"5","key":"6","first-page":"358","volume":"10","year":"2008","journal-title":"Israel Medical Association Journal"},{"issue":"2","key":"7","first-page":"269","volume":"30","year":"2012","journal-title":"Clinical and Experimental Rheumatology"},{"issue":"6","key":"8","first-page":"77","volume":"34","year":"2016","journal-title":"Clinical and Experimental Rheumatology"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1136\/adc.86.6.434"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2007.7"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-016-3317-7"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.50.4421"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2015.08.017"}],"container-title":["Case Reports in Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crirh\/2018\/6580835.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crirh\/2018\/6580835.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crirh\/2018\/6580835.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,5,2]],"date-time":"2018-05-02T19:38:52Z","timestamp":1525289932000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crirh\/2018\/6580835\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":13,"alternative-id":["6580835","6580835"],"URL":"https:\/\/doi.org\/10.1155\/2018\/6580835","relation":{},"ISSN":["2090-6889","2090-6897"],"issn-type":[{"type":"print","value":"2090-6889"},{"type":"electronic","value":"2090-6897"}],"subject":[],"published":{"date-parts":[[2018]]}}}