{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T10:41:52Z","timestamp":1753180912897,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T00:00:00Z","timestamp":1531958400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Urology"],"published-print":{"date-parts":[[2018,7,19]]},"abstract":"<jats:p>Gynecomastia is a common incidental finding in males that can be caused by various benign or malignant diseases. In rare cases, it results from Leydig cell tumors, a rare entity accounting for 3% of all testicular neoplasms. Some of them are hormonally active but seldom cause symptomatic endocrine disturbance. Here we report on a 32-year-old male presenting with gynecomastia which he had already been suffering from for two years. Although he had been seen by three other specialists, including a urologist, none of them found the small mass in the upper pole of his right testis. We decided to perform testis-sparing surgery which confirmed the diagnosis of a hormonally active Leydig cell tumor. During follow-up, hormonal status normalized, and gynecomastia began to resolve.<\/jats:p>","DOI":"10.1155\/2018\/7202560","type":"journal-article","created":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T19:40:18Z","timestamp":1532029218000},"page":"1-4","source":"Crossref","is-referenced-by-count":5,"title":["Two Years of Gynecomastia Caused by Leydig Cell Tumor"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8898-6588","authenticated-orcid":true,"given":"Philip","family":"Zeuschner","sequence":"first","affiliation":[{"name":"Department of Urology and Pediatric Urology, Saarland University, Homburg\/Saar, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Veith","sequence":"additional","affiliation":[{"name":"Department of Pathology, Saarland University, Homburg\/Saar, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Linxweiler","sequence":"additional","affiliation":[{"name":"Department of Urology and Pediatric Urology, Saarland University, Homburg\/Saar, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"St\u00f6ckle","sequence":"additional","affiliation":[{"name":"Department of Urology and Pediatric Urology, Saarland University, Homburg\/Saar, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Heinzelbecker","sequence":"additional","affiliation":[{"name":"Department of Urology and Pediatric Urology, Saarland University, Homburg\/Saar, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-018-0796-x"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-016-0975-9"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8210.129104"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp070677"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.4065\/84.11.1010"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198503000-00002"},{"issue":"2","key":"7","first-page":"164","volume":"10","year":"2008","journal-title":"Reviews in Urology"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10177.x"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-0183"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.12.012"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-014-1361-y"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1159\/000012147"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.1998.00484.x"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199811000-00006"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11573"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2008.08016.x"}],"container-title":["Case Reports in Urology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criu\/2018\/7202560.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criu\/2018\/7202560.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criu\/2018\/7202560.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T19:40:20Z","timestamp":1532029220000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criu\/2018\/7202560\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,19]]},"references-count":16,"alternative-id":["7202560","7202560"],"URL":"https:\/\/doi.org\/10.1155\/2018\/7202560","relation":{},"ISSN":["2090-696X","2090-6978"],"issn-type":[{"type":"print","value":"2090-696X"},{"type":"electronic","value":"2090-6978"}],"subject":[],"published":{"date-parts":[[2018,7,19]]}}}