{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T17:58:42Z","timestamp":1792432722322,"version":"4.5.0"},"reference-count":52,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,7,15]],"date-time":"2018-07-15T00:00:00Z","timestamp":1531612800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007771","name":"\u015al\u0105ski Uniwersytet Medyczny","doi-asserted-by":"publisher","award":["KNW-2-Z67\/D\/6\/K"],"award-info":[{"award-number":["KNW-2-Z67\/D\/6\/K"]}],"id":[{"id":"10.13039\/100007771","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007771","name":"\u015al\u0105ski Uniwersytet Medyczny","doi-asserted-by":"publisher","award":["KNW-1-026\/N\/6\/l"],"award-info":[{"award-number":["KNW-1-026\/N\/6\/l"]}],"id":[{"id":"10.13039\/100007771","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007771","name":"\u015al\u0105ski Uniwersytet Medyczny","doi-asserted-by":"publisher","award":["KNW-2-Z67\/D\/6\/K"],"award-info":[{"award-number":["KNW-2-Z67\/D\/6\/K"]}],"id":[{"id":"10.13039\/100007771","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007771","name":"\u015al\u0105ski Uniwersytet Medyczny","doi-asserted-by":"publisher","award":["KNW-1-026\/N\/6\/l"],"award-info":[{"award-number":["KNW-1-026\/N\/6\/l"]}],"id":[{"id":"10.13039\/100007771","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2018,7,15]]},"abstract":"<jats:p>\n                    Phenolic compounds constitute one of the most promising and ubiquitous groups with many biological activities. Synergistic interactions between natural phenolic compounds and antibiotics could offer a desired alternative approach to the therapies against multidrug-resistant bacteria. The objective of the presented study was to assess the antibacterial potential of caffeic acid (CA) alone and in antibiotic-phytochemical combination against\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    reference and clinical strains isolated from infected wounds. The caffeic acid tested in the presented study showed diverse effects on\n                    <jats:italic>S. aureus<\/jats:italic>\n                    strains with the minimum inhibitory concentration (MIC) varied from 256\n                    <jats:italic>\u03bc<\/jats:italic>\n                    g\/mL to 1024\n                    <jats:italic>\u03bc<\/jats:italic>\n                    g\/mL. The supplementation of Mueller-Hinton agar (MHA) with 1\/4 MIC of CA resulted in augmented antibacterial effect of erythromycin, clindamycin, and cefoxitin and to the lesser extent of vancomycin. The observed antimicrobial action of CA seemed to be rather strain than antibiotic dependent. Our data support the notion that CA alone exerts antibacterial activity against\n                    <jats:italic>S. aureus<\/jats:italic>\n                    clinical strains and has capacity to potentiate antimicrobial effect in combination with antibiotics. The synergy between CA and antibiotics demonstrates its potential as a novel antibacterial tool which could improve the treatment of intractable infections caused by multidrug-resistant strains.\n                  <\/jats:p>","DOI":"10.1155\/2018\/7413504","type":"journal-article","created":{"date-parts":[[2018,7,15]],"date-time":"2018-07-15T19:32:47Z","timestamp":1531683167000},"page":"1-9","source":"Crossref","is-referenced-by-count":171,"title":["Antimicrobial Potential of Caffeic Acid against\n                    <i>Staphylococcus aureus<\/i>\n                    Clinical Strains"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4013-6688","authenticated-orcid":true,"given":"Ma\u0142gorzata","family":"K\u0119pa","sequence":"first","affiliation":[{"name":"Department of Microbiology and Virology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, ul. Jagiello\u0144ska 4, 41-200 Sosnowiec, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Miklasi\u0144ska-Majdanik","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Virology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, ul. Jagiello\u0144ska 4, 41-200 Sosnowiec, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0334-0938","authenticated-orcid":true,"given":"Robert D.","family":"Wojtyczka","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Virology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, ul. Jagiello\u0144ska 4, 41-200 Sosnowiec, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danuta","family":"Idzik","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Virology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, ul. Jagiello\u0144ska 4, 41-200 Sosnowiec, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad","family":"Korzeniowski","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Virology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, ul. Jagiello\u0144ska 4, 41-200 Sosnowiec, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Smole\u0144-Dzirba","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Virology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, ul. Jagiello\u0144ska 4, 41-200 Sosnowiec, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6525-9767","authenticated-orcid":true,"given":"Tomasz J.","family":"W\u0105sik","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Virology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, ul. Jagiello\u0144ska 4, 41-200 Sosnowiec, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2010.0639"},{"issue":"2","key":"2","first-page":"232","volume":"6","year":"2009","journal-title":"Standardy Medyczne\/Pediatria"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2010.01.066"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2003.09.027"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-007-7427-x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.04.021"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2017.8148"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/s0924-8579(09)70541-2"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1080\/08927014.2013.845878"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1086\/644732"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/814590"},{"issue":"4","key":"12","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1128\/CMR.12.4.564","volume":"12","year":"1999","journal-title":"Clinical Microbiology Reviews"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1007\/BF02977005"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1590\/s1517-83822012000300013"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.3390\/molecules18089623"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2011.06.039"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2011.02.014"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-765X.2009.02783.x"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2012.0244"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2005.12.002"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21020244"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.3390\/molecules200813536"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.6156"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1111\/lam.12153"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2005.08.010"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3841.2007.00387.x"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1016\/j.cimid.2018.03.001"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.64205-0"},{"issue":"10","key":"29","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1128\/JCM.29.10.2240-2244.1991","volume":"29","year":"1991","journal-title":"Journal of Clinical Microbiology"},{"key":"30","year":"July 2017","journal-title":"European Committee on Antimicrobial Susceptibility Testing, version 2.01"},{"key":"31","year":"2015","journal-title":"European Committee on Antimicrobial Susceptibility Testing"},{"key":"32","year":"2017","journal-title":"European Committee on Antimicrobial Susceptibility Testing"},{"key":"33","first-page":"61","volume-title":"Susceptibility testing of antimicrobials in liquid media","year":"2005"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-9781(02)00244-9"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1590\/S1517-83822002000200014"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1590\/s0074-02762005000500018"},{"key":"37","year":"2014"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-016-1072-6"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-13-321"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-13-356"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-015-0838-6"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.682"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1021\/jf903966p"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2016.08.004"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-765X.2004.01587.x"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2008.04.044"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2014.10.011"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2004.02.028"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.3390\/molecules170910322"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1172\/jci200318535"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.3390\/ijms14011802"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-6446(02)02498-4"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2018\/7413504.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2018\/7413504.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2018\/7413504.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T19:17:04Z","timestamp":1604603824000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/bmri\/2018\/7413504\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,15]]},"references-count":52,"alternative-id":["7413504","7413504"],"URL":"https:\/\/doi.org\/10.1155\/2018\/7413504","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,15]]}}}