{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T20:43:14Z","timestamp":1740170594935,"version":"3.37.3"},"reference-count":45,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Diabetes Research"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>In patients with type 2 diabetes, sleep-disordered breathing is a widespread cause of deteriorated quality of life. However, robust prevalence estimates for sleep-disordered breathing in patients with type 2 diabetes are limited due to scarce data. We investigated sex differences in sleep-disordered breathing prevalence and its modulators in the DIACORE SDB substudy, a sample of outpatient type 2 diabetes. 721 participants were tested for sleep-disordered breathing using a two-channel sleep apnoea monitoring device. Patients were stratified according to the severity of sleep-disordered breathing, defined as an apnoea-hypopnoea index\u2009&lt;\u200915, \u226515 to 29, and \u226530 events per hour as no\/mild, moderate, and severe sleep-disordered breathing, respectively. In the 679 analysed patients (39% women, age 66\u2009\u00b1\u20099 years, body mass index 31.0\u2009\u00b1\u20095.4\u2009kg\/m<jats:sup>2<\/jats:sup>), the prevalence of sleep-disordered breathing was 34%. The prevalence of sleep-disordered breathing was higher in men than in women (41% versus 22%,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>) and increased with age (15%, 21%, and 30% in women and 35%, 40%, and 47% in men in those aged 18\u201359, 60\u201369, or \u226570, respectively; age trend<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.064<\/mml:mn><\/mml:math>in women and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.15<\/mml:mn><\/mml:math>in men). In linear regression analysis, age, BMI, and waist-hip ratio were associated with apnoea-hypopnoea index. Modulators for higher apnoea-hypopnoea index seem to be similar in men and women.<\/jats:p>","DOI":"10.1155\/2018\/7617524","type":"journal-article","created":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T23:34:33Z","timestamp":1522625673000},"page":"1-10","source":"Crossref","is-referenced-by-count":2,"title":["Sex Differences in the Prevalence and Modulators of Sleep-Disordered Breathing in Outpatients with Type 2 Diabetes"],"prefix":"10.1155","volume":"2018","author":[{"given":"T.","family":"Kroner","sequence":"first","affiliation":[{"name":"Department of Internal Medicine II, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Arzt","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine II, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Rheinberger","sequence":"additional","affiliation":[{"name":"Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Gorski","sequence":"additional","affiliation":[{"name":"Department of Genetic Epidemiology, University of Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. 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