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An unresolved problem is the functional assessment of intermediate lesions, as far as various target organs have quite different circulation from the coronary one and the functional tests should be modified in order to be applicable and meaningful. In the majority of the acute vascular syndromes, the culprit lesion is of intermediate size on visual assessment. On the other hand, a procedurally successfully managed high-degree stenosis is not always followed by clinical and prognostic benefit. In vascular beds, where collateral network naturally exists, the readings from the functional assessment are complicated and thus the decision for interventional treatment is even more difficult. Here come into help the functional assessment and imaging with IVUS, OCT, high-resolution MRI, and contrast enhanced CT or SPECT. The focus of the current review is on the functional assessment of intermediate stenosis in other vascular beds, unlike the coronary arteries.<\/jats:p>","DOI":"10.1155\/2018\/7619092","type":"journal-article","created":{"date-parts":[[2018,4,15]],"date-time":"2018-04-15T19:32:31Z","timestamp":1523820751000},"page":"1-9","source":"Crossref","is-referenced-by-count":2,"title":["Functional Assessment of Intermediate Vascular Disease"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1668-1432","authenticated-orcid":true,"given":"Teodora","family":"Yaneva-Sirakova","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Cardiology Clinic, Medical University Sofia, Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivanichka","family":"Serbezova","sequence":"additional","affiliation":[{"name":"\u201cAngel Kanchev\u201d University of Ruse, Ruse, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dobrin","family":"Vassilev","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Cardiology Clinic, Medical University Sofia, Sofia, Bulgaria"},{"name":"\u201cAngel Kanchev\u201d University of Ruse, Ruse, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"22","key":"1","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1093\/eurheartj\/ehr211","volume":"32","year":"2011","journal-title":"European Heart Journal"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000470"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00985.2009"},{"issue":"2","key":"4","first-page":"109","volume":"13","year":"1994","journal-title":"International Angiology"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(64)90208-6"},{"issue":"12","key":"6","first-page":"1471","volume":"82","year":"2010","journal-title":"American Family Physician"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.10.046"},{"key":"8","volume":"47","year":"2006","journal-title":"Journal of the American College of Cardiology"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm631"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000135448.73199.75"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000168052.00426.65"},{"issue":"2","key":"12","first-page":"R208","volume":"17","year":"1985","journal-title":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00051.2003"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21095"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000153271.77341.9F"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e32833ec392"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw460"},{"issue":"3","key":"18","first-page":"258","volume":"25","year":"2005","journal-title":"Nefrologia"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2002.120769"},{"key":"20","first-page":"54","volume":"76","year":"1970","journal-title":"Journal of Laboratory and Clinical Medicine"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.7.642"},{"key":"22","first-page":"1572","volume":"106","year":"2002","journal-title":"American Heart Association. 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