{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:02:30Z","timestamp":1740171750292,"version":"3.37.3"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002842","name":"Chiang Mai University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002842","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parkinson's Disease"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Previous studies have shown that Parkinson\u2019s disease (PD) patients who have REM behavior disorder (PD with RBD) might be a PD subtype since they have different symptom clusters and disease trajectories from PD without RBD. <jats:italic>Objective<\/jats:italic>. To study the prevalence of PD with pRBD and to compare the clinical characteristics with PD without pRBD. The feasibility of clinical interview of items adopted from the Mayo Sleep Questionnaire was also to be determined. <jats:italic>Methods<\/jats:italic>. A total of 140 Parkinson's patients visiting neurological clinics during January to December 2016 were enrolled in this study. \u201cProbable RBD (pRBD)\u201d was defined as present when the patient answered \u201cyes\u201d to a question adapted from the first Mayo Sleep Questionnaire (MSQ). The demographic data, motor symptoms, and nonmotor symptoms were obtained. <jats:italic>Results<\/jats:italic>. The prevalence of pRBD among this study\u2019s PD patients was 48.5% (68 out of the total of 140). The median onset of RBD before PD diagnosis was 5 years (range: 0\u201311 years). By comparison of PD with pRBD and PD without pRBD, this study showed significant difference in the levodopa equivalent dose (742\u2009mg\/day versus 566\u2009mg\/day; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:mrow><\/mml:math>), prevalence of symptomatic orthostatic hypotension (35.3% versus 8.3%; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:mrow><\/mml:math>). The multivariable analysis found that pRBD is independently associated with orthostatic hypotension (OR\u2009=\u20095.02, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:mrow><\/mml:math>). Conclusion. The findings regarding prevalence and main clinical features of PD with pRBD in this study were similar to those of a previous study of PD with polysomnogram- (PSG-) proven RBD. This study hypothesized that interviewing by adopted MSQ may be a cost-effective tool for screening RBD. Further studies with direct comparison are needed.<\/jats:p>","DOI":"10.1155\/2018\/7657191","type":"journal-article","created":{"date-parts":[[2018,2,4]],"date-time":"2018-02-04T18:31:50Z","timestamp":1517769110000},"page":"1-6","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence and Clinical Characteristics of Probable REM Behavior Disorder in Thai Parkinson\u2019s Disease Patients"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7360-8979","authenticated-orcid":true,"given":"Patama","family":"Gomutbutra","sequence":"first","affiliation":[{"name":"Division of Neurology, Department and Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kittika","family":"Kanjanaratanakorn","sequence":"additional","affiliation":[{"name":"Research Administration Section, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5398-745X","authenticated-orcid":true,"given":"Nantaporn","family":"Tiyapun","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department and Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/17.4.378"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.05115.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25037"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2010.12.009"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1590\/0004-282x20140228"},{"issue":"2","key":"6","first-page":"163","volume":"19","year":"2014","journal-title":"Neurology Asia"},{"issue":"2","key":"7","first-page":"S159","volume":"97","year":"2014","journal-title":"Journal of the Medical Association of Thailand"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25086"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1038\/srep40779"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23429"},{"year":"2017","key":"11"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1056\/nejmcp074189"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2008.01602.x"},{"key":"14","first-page":"9","volume":"1","year":"2006","journal-title":"Archives of Orofacial Sciences"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2013.00064"},{"issue":"3","key":"16","first-page":"S68","volume":"97","year":"2014","journal-title":"Journal of the Medical Association of Thailand"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.0b013e31822e560e"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2010.08.011"},{"journal-title":"Journal of Clinical Neuroscience","year":"2017","key":"19"},{"issue":"1","key":"20","first-page":"644","volume":"28","year":"2013","journal-title":"Movement Disorders"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25856"}],"container-title":["Parkinson's Disease"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/pd\/2018\/7657191.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/pd\/2018\/7657191.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/pd\/2018\/7657191.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,5]],"date-time":"2018-03-05T18:32:16Z","timestamp":1520274736000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/pd\/2018\/7657191\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":21,"alternative-id":["7657191","7657191"],"URL":"https:\/\/doi.org\/10.1155\/2018\/7657191","relation":{},"ISSN":["2090-8083","2042-0080"],"issn-type":[{"type":"print","value":"2090-8083"},{"type":"electronic","value":"2042-0080"}],"subject":[],"published":{"date-parts":[[2018]]}}}