{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T20:30:02Z","timestamp":1740169802251,"version":"3.37.3"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. The middle ear is an air-filled lacuna in the temporal bone. Inhaled anesthetic agents increase the pressure of this lacuna. Therefore, attention must be paid in choosing not only anesthetic agents but also anesthetic method.<jats:italic> Aim<\/jats:italic>. This study compared the effects of high-flow total intravenous anesthesia (TIVA) and low- and high-flow desflurane anesthesia on middle ear pressure.<jats:italic> Study Design<\/jats:italic>. Randomized prospective double-blind study.<jats:italic> Methods<\/jats:italic>. In this retrospective double-blind study, 90 patients (20\u201365 years old) scheduled to undergo elective thyroidectomies were divided into three randomized anesthesia groups: high-flow desflurane (Group I), low-flow desflurane (Group II), and high-flow TIVA (propofol, remifentanil) (Group III). The hemodynamic and respiratory parameters and tympanometry were measured before induction (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>1), 10 minutes after intubation (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>2), 10 minutes before the end of the operation (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>3), and 5 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>4), 10 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>5), 15 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>6), and 30 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>7) minutes after the operation.<jats:italic> Results<\/jats:italic>. No statistically significant differences were found in the age, gender, weight, height, body mass index, surgery duration, and anesthetic duration (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mi>p<\/mml:mi><mml:mo>&gt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.05<\/mml:mn><\/mml:math>). There were no statistically significant differences at <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>1, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>3, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>4, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M12\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>5, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M13\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>6, and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M14\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>7 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M15\"><mml:mi>p<\/mml:mi><mml:mo>&gt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.007<\/mml:mn><\/mml:math>), but there was a significant difference at <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M16\"><mml:mrow><mml:mi>T<\/mml:mi><\/mml:mrow><\/mml:math>2 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M17\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.001<\/mml:mn><\/mml:math>), with Groups II and III having lower pressure than Group I (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M18\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.001<\/mml:mn><\/mml:math>).<jats:italic> Conclusion<\/jats:italic>. The high-flow desflurane group had higher postinduction middle ear pressure values. Therefore, low-flow anesthesia and TIVA can be used more safely in middle ear surgeries, provided that a well-equipped anesthetic device and appropriate monitoring conditions are available.<\/jats:p>","DOI":"10.1155\/2018\/8214651","type":"journal-article","created":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T19:37:40Z","timestamp":1523389060000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["Effects of Total Intravenous Anesthesia and Low- and High-Flow Anesthesia Implementation on Middle Ear Pressure"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9881-8534","authenticated-orcid":true,"given":"Ayca Dumanli","family":"Ozcan","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aysun Ersen","family":"Yungul","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Togay","family":"Muderris","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Ankara Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hulya","family":"Kasikara","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Helin Sahinturk","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orhan","family":"Kanbak","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Ankara Atat\u00fcrk Training and Research Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulkadir","family":"But","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Reanimation, Y\u0131ld\u0131r\u0131m Beyaz\u0131t University, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198210000-00017"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1980.tb01539.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/00003643-199601000-00006"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199703000-00015"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2007.05.022"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2005.12.020"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.5152\/TJAR.2012.011"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s005400050050"},{"issue":"6","key":"10","first-page":"285","volume":"30","year":"2010","journal-title":"Acta Otorinorhinolaryngologica Italica"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.17219\/acem\/37144"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2018\/8214651.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2018\/8214651.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2018\/8214651.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T19:37:40Z","timestamp":1523389060000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/bmri\/2018\/8214651\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":10,"alternative-id":["8214651","8214651"],"URL":"https:\/\/doi.org\/10.1155\/2018\/8214651","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"type":"print","value":"2314-6133"},{"type":"electronic","value":"2314-6141"}],"subject":[],"published":{"date-parts":[[2018]]}}}