{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:36:39Z","timestamp":1761863799336,"version":"3.37.3"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p><jats:italic>Objective.<\/jats:italic> To test whether or not the modified design of the test implant (intended to increase primary stability) has an equivalent effect on MBL compared to the control.<jats:italic> Methods. <\/jats:italic>Forty patients were randomly assigned to receive test or control implants to be installed in identically dimensioned bony beds. Implants were radiographically monitored at installation, at prosthetic delivery, and after one year. Treatments were considered equivalent if the 90% confidence interval (CI) for the mean difference (MD) in MBL was in between \u22120.25 and 0.25\u2009mm. Additionally, several soft tissue parameters and patient-reported outcome measures (PROMs) were evaluated. Linear mixed models were fitted for each patient to assess time effects on response variables.<jats:italic> Results.<\/jats:italic> Thirty-three patients (21 males, 12 females; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn fontstyle=\"italic\">58.2<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">15.2<\/mml:mn><\/mml:math> years old) with 81 implants (47 test, 34 control) were available for analysis after a mean observation period of <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn fontstyle=\"italic\">13.9<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">4.5<\/mml:mn><\/mml:math> months (3 dropouts, 3 missed appointments, and 1 missing file). The adjusted MD in MBL after one year was \u22120.13\u2009mm (90% CI: \u22120.46\u20130.19; test group: \u22120.49; control group: \u22120.36; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.507<\/mml:mn><\/mml:math>).<jats:italic> Conclusion.<\/jats:italic> Both implant systems can be considered successful after one year of observation. Concerning MBL in the presented setup, equivalence of the treatments cannot be concluded.<jats:italic> Registration<\/jats:italic>. This trial is registered with the German Clinical Trials Register (ID: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.drks.de\/drks_web\/navigate.do?navigationId=trial.HTML&amp;TRIAL_ID=DRKS00007877\">DRKS00007877<\/jats:ext-link>).<\/jats:p>","DOI":"10.1155\/2018\/8436437","type":"journal-article","created":{"date-parts":[[2018,1,31]],"date-time":"2018-01-31T18:36:37Z","timestamp":1517423797000},"page":"1-11","source":"Crossref","is-referenced-by-count":9,"title":["Does Oral Implant Design Affect Marginal Bone Loss? Results of a Parallel-Group Randomized Controlled Equivalence Trial"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1702-1679","authenticated-orcid":true,"given":"Benedikt C.","family":"Spies","sequence":"first","affiliation":[{"name":"Department of Prosthetic Dentistry, Center for Dental Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"},{"name":"Department of Prosthodontics, Geriatric Dentistry and Craniomandibular Disorders, Charit\u00e9 Center for Dental and Craniofacial Sciences (CC3), Charit\u00e9-Universit\u00e4tsmedizin Berlin, Campus Benjamin Franklin (CBF), Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Bateli","sequence":"additional","affiliation":[{"name":"Department of Prosthetic Dentistry, Center for Dental Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"},{"name":"Private Practice, Freiburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghada","family":"Ben Rahal","sequence":"additional","affiliation":[{"name":"Department of Prosthetic Dentistry, Center for Dental Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marin","family":"Christmann","sequence":"additional","affiliation":[{"name":"Department of Prosthetic Dentistry, Center for Dental Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirstin","family":"Vach","sequence":"additional","affiliation":[{"name":"University Medical Center Freiburg, Center for Medical Biometry and Medical Informatics, Institute for Medical Biometry and Statistics, Freiburg, 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