{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:13:29Z","timestamp":1740165209852,"version":"3.37.3"},"reference-count":11,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Ophthalmological Medicine"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>Carcinoma of the conjunctiva is a malignant tumor which is mostly detected and surgically treated at an early stage because of medical or cosmetic problems. Exceptions of this rule may occur in developing countries, where patients do not have access to standard medical care systems. We report the case of a conjunctival carcinoma in an African patient with an unusually late presentation. Because of local medical shortcomings, and considering the severe, transmural inflammation of anterior ocular structures, an exenteration was performed although the orbit was not deeply involved with the tumor. The strong nuclear expression of p53 indicates a major role of UV exposure in this case. A total of 16-month follow-up in this patient and larger published series suggest that the risk of metastasis is rather low under those circumstances, even with invasive tumors.<\/jats:p>","DOI":"10.1155\/2018\/8461737","type":"journal-article","created":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T19:34:17Z","timestamp":1522611257000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["Treatment and Pathology of an Unusual Large Carcinoma of the Conjunctiva"],"prefix":"10.1155","volume":"2018","author":[{"given":"Thomas","family":"Stahnke","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Rostock University Medical Center, Doberaner Stra\u00dfe 140, 18057 Rostock, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ngoy","family":"Kilangalanga","sequence":"additional","affiliation":[{"name":"Eye Department, Hospital Saint Joseph, 322 Limete, Kinshasa, Democratic Republic of the Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffi","family":"Knappe","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Rostock University Medical Center, Doberaner Stra\u00dfe 140, 18057 Rostock, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolf F.","family":"Guthoff","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Rostock University Medical Center, Doberaner Stra\u00dfe 140, 18057 Rostock, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2624-7362","authenticated-orcid":true,"given":"Andreas","family":"Erbersdobler","sequence":"additional","affiliation":[{"name":"Institute of Pathology, Rostock University Medical Center, Strempelstra\u00dfe 14, 18055 Rostock, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","first-page":"73","volume":"6","year":"1997","journal-title":"Cancer Epidemiology, Biomarkers & Prevention"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.12203"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.12792"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2014.10.015"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000581"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1997.01100150290029"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)00177-3"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.118.9.1296"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s00347-003-0960-6"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.83.1.98"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_983_16"}],"container-title":["Case Reports in Ophthalmological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2018\/8461737.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2018\/8461737.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2018\/8461737.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T19:34:17Z","timestamp":1522611257000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criopm\/2018\/8461737\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":11,"alternative-id":["8461737","8461737"],"URL":"https:\/\/doi.org\/10.1155\/2018\/8461737","relation":{},"ISSN":["2090-6722","2090-6730"],"issn-type":[{"type":"print","value":"2090-6722"},{"type":"electronic","value":"2090-6730"}],"subject":[],"published":{"date-parts":[[2018]]}}}