{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:58:26Z","timestamp":1740149906689,"version":"3.37.3"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,9,20]],"date-time":"2018-09-20T00:00:00Z","timestamp":1537401600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2015R1A5A2009656","0920050"],"award-info":[{"award-number":["NRF-2015R1A5A2009656","0920050"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["NRF-2015R1A5A2009656","0920050"],"award-info":[{"award-number":["NRF-2015R1A5A2009656","0920050"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology Research and Practice"],"published-print":{"date-parts":[[2018,9,20]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Chronic gastric anisakiasis is a rare, usually asymptomatic, and difficult to diagnose infection incidentally discovered during endoscopy, resembling a subepithelial tumor (SET). Because its endoscopic ultrasonography (EUS) findings are not established, it is occasionally misdiagnosed as gastrointestinal mesenchymal tumors and removed by endoscopic or surgical resection. We aimed to assess the characteristic EUS findings of chronic gastric anisakiasis and the clinical course during follow-up. <jats:italic>Methods<\/jats:italic>. The database of all patients who underwent EUS at Pusan National University Hospital (Busan, Korea) between January 2011 and December 2016 was retrospectively analyzed. A total of 28 SET cases with EUS features suggesting chronic gastric anisakiasis were included in the study. The EUS, histopathologic, and follow-up endoscopic features were analyzed. <jats:italic>Results<\/jats:italic>. On EUS, the lesions were mainly located in the submucosal and\/or propria muscle layers. Twenty-seven lesions (27\/28, 96%) showed hypoechoic echogenicity, and 22 lesions (22\/28, 79%) were heterogeneous. Hyperechoic tubular structures suggesting denaturalized Anisakidae larvae were seen in 22 lesions (22\/28, 79%). Endoscopic biopsies revealed significant eosinophil infiltration (\u226530 per high-power field) in 12 lesions (12\/21, 57%). During the median follow-up period of 9 months (range, 1\u201355 months), SETs decreased or subsided in 26 lesions (26\/28, 93%) with no change in the size of the two lesions (2\/28, 7%). <jats:italic>Conclusions<\/jats:italic>. Chronic gastric anisakiasis, although rare, should be included in the differential diagnoses for gastric SETs, especially in regions where raw fish is widely consumed. EUS findings suggesting chronic gastric anisakiasis are heterogeneously hypoechoic lesions with hyperechoic tubular structures, mainly in the submucosal and\/or muscularis propria layers. Because chronic gastric anisakiasis decreases or subsides in most cases, follow-up endoscopy 6\u201312 months later is recommended.<\/jats:p>","DOI":"10.1155\/2018\/8562792","type":"journal-article","created":{"date-parts":[[2018,9,20]],"date-time":"2018-09-20T19:34:43Z","timestamp":1537472083000},"page":"1-7","source":"Crossref","is-referenced-by-count":4,"title":["Endosonographic Findings and the Natural Course of Chronic Gastric Anisakiasis: A Single-Center Experience"],"prefix":"10.1155","volume":"2018","author":[{"given":"Eun Young","family":"Park","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Pusan National University School of Medicine, and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong Hoon","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Pusan National University School of Medicine, and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9721-5734","authenticated-orcid":true,"given":"Gwang Ha","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Pusan National University School of Medicine, and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bong Eun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Pusan National University School of Medicine, and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"So-Jeong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pathology, Pusan National University School of Medicine, Busan, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Do Youn","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Pathology, Pusan National University School of Medicine, Busan, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","first-page":"97","volume":"12","year":"1960","journal-title":"Tropical and Geographical Medicine"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(89)72797-8"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.2006.44.1.81"},{"issue":"6","key":"4","first-page":"381","volume":"32","year":"2006","journal-title":"Korean Journal of Gastrointestinal Endoscopy"},{"key":"5","first-page":"267","volume":"30","year":"2005","journal-title":"Korean Journal of Gastrointestinal 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