{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:51:18Z","timestamp":1762005078237,"version":"3.37.3"},"reference-count":47,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,11,18]],"date-time":"2018-11-18T00:00:00Z","timestamp":1542499200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2018,11,18]]},"abstract":"<jats:p>Extra-intestinal<jats:italic> E. coli<\/jats:italic> are emerging as a global threat due to their diffusion as opportunistic pathogens and, above all, to their wide set of antibiotic resistance determinants. There are still many gaps in our knowledge of their origin and spread pathways, although food animals have been adjudicated vehicles for passing mult-drug resistant bacteria to humans. This study analyzed 46 samples of meat purchased from retail stores in Palermo in order to obtain quinolone-resistant<jats:italic> E. coli<\/jats:italic> isolates. Strains were screened for their phylogenetic groups, ST131-associated single nucleotide polymorphisms (SNPs), and then typed by ERIC-PCR. Their set of virulence factors, namely,<jats:italic> kpsMII, papA, sfaS, focG, iutA, papC, hlyD<\/jats:italic>, and<jats:italic> afa<\/jats:italic> genes, were investigated and their fluoroquinolone-resistance determinants evaluated. The data obtained show a dramatically high prevalence of multidrug resistance patterns in the Palermo area, with 28% of the isolates having virulence factor genes typical of ExPEC strains. No B2 group or ST131 strains were detected. Moreover, 20% of our isolates showed positivity to all the plasmid-mediated quinolone resistance (PMQR) determinants, showing a potential to transfer these genes among other bacteria. Therefore, these data underline the possibility that food animals and, specifically, poultry in particular may be a significant source of resistant bacterial strains, posing a potential zoonotic risk.<\/jats:p>","DOI":"10.1155\/2018\/8714975","type":"journal-article","created":{"date-parts":[[2018,11,18]],"date-time":"2018-11-18T18:39:43Z","timestamp":1542566383000},"page":"1-7","source":"Crossref","is-referenced-by-count":12,"title":["Extra-Intestinal Fluoroquinolone-Resistant Escherichia coli Strains Isolated from Meat"],"prefix":"10.1155","volume":"2018","author":[{"given":"Giorgia","family":"Caruso","sequence":"first","affiliation":[{"name":"Department of Sciences for Health Promotion and Mother & Child Care, University of Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Giammanco","sequence":"additional","affiliation":[{"name":"Department of Sciences for Health Promotion and Mother & Child Care, University of Palermo, 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