{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:11:56Z","timestamp":1767651116613,"version":"3.37.3"},"reference-count":8,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,6,10]],"date-time":"2018-06-10T00:00:00Z","timestamp":1528588800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Otolaryngology"],"published-print":{"date-parts":[[2018,6,10]]},"abstract":"<jats:p>Malignant peripheral nerve sheath tumor (MPNST) is a rare disease in the parotid gland with a poor prognosis in most cases. The disease most often develops in the setting of neurofibromatosis type 1 (NF1) but can also occur sporadically. Herein, we report a rare case of MPNST in the parotid gland, in a patient with no previous history of NF1. Initial investigations of the patient, which consisted of laboratory investigations, ultrasound imaging of the swelling, fine-needle aspiration (FNA), computed tomography (CT) scan, and magnetic resonance imaging (MRI) of the neck and swelling, were compatible with a benign pleomorphic adenoma of the parotid gland. However, intraoperatively, the dissection was challenging as the tumor was adherent to the neighboring tissue. A diagnosis of MPNST arising from a diffuse neurofibroma was established based on clinicopathologic features of the disease. The patient, who exhibited clinical features compatible with (NF1), proceeded for radiotherapy following surgery to continue his treatment.<\/jats:p>","DOI":"10.1155\/2018\/8768472","type":"journal-article","created":{"date-parts":[[2018,6,10]],"date-time":"2018-06-10T19:32:12Z","timestamp":1528659132000},"page":"1-5","source":"Crossref","is-referenced-by-count":3,"title":["Diffuse Neurofibroma in a Patient with Unknown History of NF1"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7060-6513","authenticated-orcid":true,"given":"Mahmoud A. K.","family":"Ebrahim","sequence":"first","affiliation":[{"name":"Farwaniya Hospital, Ministry of Health, Kuwait City, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mishal M.","family":"AlMutairi","sequence":"additional","affiliation":[{"name":"Zain Hospital, Ministry of Health, Kuwait City, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaled M.","family":"Hindi","sequence":"additional","affiliation":[{"name":"Kuwait Institute Medical Specialties, Kuwait City, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7438-9870","authenticated-orcid":true,"given":"Jassem M.","family":"Bastaki","sequence":"additional","affiliation":[{"name":"Al-Sabah Hospital, Ministry of Health, Kuwait City, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/scs.0000000000000938"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20537"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.4172\/2165-7920.1000243"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0000000000000447"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnci.2016.11.001"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2013.11.012"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.56.11.826"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2013-0328"}],"container-title":["Case Reports in Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2018\/8768472.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2018\/8768472.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2018\/8768472.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,6,10]],"date-time":"2018-06-10T19:32:13Z","timestamp":1528659133000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/criot\/2018\/8768472\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,10]]},"references-count":8,"alternative-id":["8768472","8768472"],"URL":"https:\/\/doi.org\/10.1155\/2018\/8768472","relation":{},"ISSN":["2090-6765","2090-6773"],"issn-type":[{"type":"print","value":"2090-6765"},{"type":"electronic","value":"2090-6773"}],"subject":[],"published":{"date-parts":[[2018,6,10]]}}}