{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:50:50Z","timestamp":1756385450557,"version":"3.37.3"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2018,7,11]],"date-time":"2018-07-11T00:00:00Z","timestamp":1531267200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Endocrinology"],"published-print":{"date-parts":[[2018,7,11]]},"abstract":"<jats:p>Ectopic thyroid tissue is a rare clinical entity wherein malignant lesions may arise, the most common one being papillary carcinoma. We present a case of a 68-year-old female who presented with a growing mass in the right clavicle. An MR of the shoulder showed a soft tissue mass arising from the anterior margin of the right distal clavicle. A fine needle aspiration of the mass showed papillary thyroid carcinoma. PET\/CT confirmed the clavicular and mediastinal mass. Excision of the clavicular mass and total thyroidectomy with modified right neck dissection were performed. Pathology revealed no evidence of malignancy in the thyroid; lymph nodes were positive for metastatic thyroid carcinoma. Postsurgery CT showed the superior mediastinal mass with surrounding adenopathy; radioiodine (RAI) treatment with dose of 142.1 mCi [5257.7 MBq] was recommended. Posttherapy whole-body scan (WBS) showed RAI avid tissue in the neck and superior mediastinum. Follow-up chest CT revealed pulmonary nodules that increased in number and size; a second RAI therapeutic dose was given. The posttherapy RAI WBS was negative. Repeat PET\/CT showed multiple hypermetabolic lesions in the mediastinum, neck, lymph nodes, pulmonary nodes, and right shoulder. The FDG avid lesions with no RAI uptake suggested tumor dedifferentiation.<\/jats:p>","DOI":"10.1155\/2018\/8956712","type":"journal-article","created":{"date-parts":[[2018,7,11]],"date-time":"2018-07-11T19:55:11Z","timestamp":1531338911000},"page":"1-4","source":"Crossref","is-referenced-by-count":5,"title":["Ectopic Papillary Thyroid Cancer with Distant Metastasis"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0354-6263","authenticated-orcid":true,"given":"Oscar R.","family":"V\u00e1zquez","sequence":"first","affiliation":[{"name":"Nuclear Medicine Section, Radiological Sciences Department, University of Puerto Rico, San Juan, Puerto Rico, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frieda","family":"Silva","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Section, Radiological Sciences Department, University of Puerto Rico, San Juan, Puerto Rico, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Acosta-Pumarejo","sequence":"additional","affiliation":[{"name":"Radiology Department, VA Caribbean Healthcare System, San Juan, Puerto Rico, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria L.","family":"Mar\u00edn","sequence":"additional","affiliation":[{"name":"Pathology Department, Isaac Gonzalez Oncologic Hospital, San Juan, Puerto Rico, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"4","key":"1","first-page":"114","volume":"34","year":"2013","journal-title":"Giornale di Chirurgia"},{"journal-title":"ISRN Surgery","year":"2011","key":"2"},{"key":"3","first-page":"121","volume-title":"Thyroid cancer\u2014indications and opportunities for positron emission tomography\/computed tomography imaging","volume":"41, no. 2","year":"2011"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(16)46082-2"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2012.11.014"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9707031"},{"issue":"2","key":"7","first-page":"122","volume":"13","year":"2007","journal-title":"Annals of Thoracic and Cardiovascular Surgery"},{"issue":"1, article 67","key":"8","volume":"32","year":"2016","journal-title":"Turkish Journal of Surgery\/Ulusal Cerrahi Dergisi"},{"issue":"1, article 44","key":"9","volume":"1","year":"2013","journal-title":"Journal of Nuclear Medicine and Biology"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2015-0107"}],"container-title":["Case Reports in Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2018\/8956712.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2018\/8956712.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crie\/2018\/8956712.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,7,11]],"date-time":"2018-07-11T19:55:14Z","timestamp":1531338914000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crie\/2018\/8956712\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,11]]},"references-count":10,"alternative-id":["8956712","8956712"],"URL":"https:\/\/doi.org\/10.1155\/2018\/8956712","relation":{},"ISSN":["2090-6501","2090-651X"],"issn-type":[{"type":"print","value":"2090-6501"},{"type":"electronic","value":"2090-651X"}],"subject":[],"published":{"date-parts":[[2018,7,11]]}}}