{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:23:59Z","timestamp":1762475039863,"version":"build-2065373602"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,6,24]],"date-time":"2018-06-24T00:00:00Z","timestamp":1529798400000},"content-version":"vor","delay-in-days":174,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:p>Sirenomelia is a rare developmental malformation and is incompatible to life. The incidence of sirenomelia, as recorded in the literature, is estimated to be approximately between 1.5 and 4.2 per 1,00,000 births. Around 15% of sirenomelia cases are associated with twin pregnancy, most often in monozygotic cases with an incidence of 7%. In monozygotic twins, the risk of sirenomelia is nearly 100\u2013150 times higher as compared to dizygotic twins or singleton pregnancies. Until now, only two cases of sirenomelia associated with hypoplastic left heart have been reported in the literature. Here, we present a monozygotic twin pregnancy, where one fetus was diagnosed with sirenomelia associated with hypoplastic left heart syndrome and the co\u2010twin was absolutely healthy.<\/jats:p>","DOI":"10.1155\/2018\/9361745","type":"journal-article","created":{"date-parts":[[2018,6,24]],"date-time":"2018-06-24T19:32:09Z","timestamp":1529868729000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Case of Sirenomelia Associated with Hypoplastic Left Heart with a Healthy Co\u2010Twin: A Rare Entity"],"prefix":"10.1155","volume":"2018","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5464-6136","authenticated-orcid":false,"given":"Houda Nasser","family":"Al Yaqoubi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muna Mubarak","family":"Al Badi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farida Mohsin","family":"Ambu Saidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasser Shaikhan Taaeeb","family":"Al Shafouri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,6,24]]},"reference":[{"key":"e_1_2_6_1_2","first-page":"42","article-title":"A prenatally diagnosed case of sirenomelia with dextrocardia and omphalocele","volume":"3","author":"Cavaliere A.","year":"2009","journal-title":"Journal of Prenatal Medicine"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.4103\/2249-4847.106006"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2007.26.1.97"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33599"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1989.8.2.83"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1515\/bjmg-2017-0001"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.4274\/tjod.90688"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.10983"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2005.24.11.1555"},{"key":"e_1_2_6_10_2","first-page":"138","article-title":"Sirenomelia in a monoamniotic twin: a case report","volume":"51","author":"Akl M. N.","year":"2006","journal-title":"Journal of Reproductive Medicine"},{"key":"e_1_2_6_11_2","article-title":"Sirenomelia in an Iraqi twin: a case report","volume":"5757","author":"Hassan M. A.","year":"2015","journal-title":"Journal of the Faculty of Medicine, Baghdad"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.4137\/CCRep.S5347"}],"container-title":["Case Reports in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2018\/9361745.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2018\/9361745.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2018\/9361745","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:18:57Z","timestamp":1762474737000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2018\/9361745"}},"subtitle":[],"editor":[{"given":"Alexander K. C.","family":"Leung","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1155\/2018\/9361745"],"URL":"https:\/\/doi.org\/10.1155\/2018\/9361745","archive":["Portico"],"relation":{},"ISSN":["2090-6803","2090-6811"],"issn-type":[{"type":"print","value":"2090-6803"},{"type":"electronic","value":"2090-6811"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"2018-02-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"9361745"}}