{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T01:38:11Z","timestamp":1788917891200,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Respiratory Journal"],"published-print":{"date-parts":[[2019,4,1]]},"abstract":"<jats:p><jats:italic>Aim<\/jats:italic>. To analyze the radiological, clinical, and prognostic features of primary pulmonary salivary gland-type tumors (SGTs) and improve their diagnosis. <jats:italic>Materials and Methods<\/jats:italic>. We retrospectively collected clinical and pathological data for 32 SGT cases confirmed by pathology and analyzed their radiological features, clinical presentations, and treatment outcomes. <jats:italic>Results<\/jats:italic>. Mucoepidermoid carcinoma (MEC) was more likely to occur in younger patients than was adenoid cystic carcinoma (ACC) (35\u2009\u00b1\u200915\u2009years vs 48\u2009\u00b1\u200916\u2009years, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.038<\/mml:mn><\/mml:mrow><\/mml:math>). MEC was equally distributed between both sexes, whereas ACC was more frequent in females (66.7%). The main presenting symptom of SGT was cough (56.3%), followed by dyspnea (40.6%), associated with the tumor location. ACC more frequently involved the trachea or main bronchus (86.7% vs 25.0%, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>) and more commonly presented as lobulated or circumferential thickening than MEC (93.3% vs 37.5%, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.002<\/mml:mn><\/mml:mrow><\/mml:math>). MEC more frequently presented as obvious enhancement than ACC (68.8% vs 31.3%, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>). CT findings suggestive of airway obstructive disease were more likely to be observed with MEC than ACC (73.3% vs 25.0%; <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.021<\/mml:mn><\/mml:mrow><\/mml:math>). The SUVmax in 8 of 10 patients with PET\/CT data exceeded 2.2 but was less than 6.0. The overall survival (OS) at 3 and 5\u2009years was 90.9% and 72.2% in all patients, respectively. Tumor-node-metastasis (TNM) stage, surgery, and patient age were associated with OS (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>\u2264<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>, and <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:mrow><\/mml:math>, respectively). <jats:italic>Conclusion<\/jats:italic>. SGTs commonly occur in patients at a young age and are associated with weak invasive features and a good prognosis. The predominant site and CT characteristics are significantly different between ACC and MEC.<\/jats:p>","DOI":"10.1155\/2019\/1475024","type":"journal-article","created":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T19:31:41Z","timestamp":1554147101000},"page":"1-10","source":"Crossref","is-referenced-by-count":11,"title":["Radiological and Clinical Features and Outcomes of Patients with Primary Pulmonary Salivary Gland-Type Tumors"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6121-596X","authenticated-orcid":true,"given":"Xiaoyu","family":"Han","sequence":"first","affiliation":[{"name":"Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Rd, Wuhan, Hubei Province 430022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianchu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Union Hospital, Tongji Medical Collage, Huazhong University of Science and Technology, 1277 Jiefang Rd, Wuhan, Hubei Province 430022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Pathology, Union Hospital, Tongji Medical Collage, Huazhong University of Science and Technology, 1277 Jiefang Rd, Wuhan, Hubei Province 430022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukun","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Rd, Wuhan, Hubei Province 430022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7993-218X","authenticated-orcid":true,"given":"Jin","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Rd, Wuhan, Hubei Province 430022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0877-3054","authenticated-orcid":true,"given":"Heshui","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Rd, Wuhan, Hubei Province 430022, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/pap.0000000000000099"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/jto.0b013e3182a7d272"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.12.9579"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.177.5.1771145"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23048"},{"key":"6","year":"2015"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.212.3.r99se09643"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.183.2.1830277"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2007.08.022"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2011.03.003"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2017.02.007"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199809000-00006"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870915)60:6<1346::aid-cncr2820600631>3.0.co;2-0"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2010.08.021"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2016.11.24"},{"issue":"2","key":"16","first-page":"106","volume":"12","year":"1995","journal-title":"Seminars in Diagnostic Pathology"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.3941\/jrcr.v11i2.3061"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-10-232"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1259\/bjrcr.20150201"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/s0899-7071(01)00317-5"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.07.2652"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.1.452"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2018.00153"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1378\/chest.100.5.1464"}],"container-title":["Canadian Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2019\/1475024.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2019\/1475024.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2019\/1475024.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T19:31:43Z","timestamp":1554147103000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crj\/2019\/1475024\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,1]]},"references-count":24,"alternative-id":["1475024","1475024"],"URL":"https:\/\/doi.org\/10.1155\/2019\/1475024","relation":{},"ISSN":["1198-2241","1916-7245"],"issn-type":[{"value":"1198-2241","type":"print"},{"value":"1916-7245","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,1]]}}}