{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:55:51Z","timestamp":1792277751078,"version":"4.4.0"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T00:00:00Z","timestamp":1554163200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Tropical Medicine"],"published-print":{"date-parts":[[2019,4,2]]},"abstract":"<jats:p>\n                    The emergence and spread of antibiotic resistance, as well as the evolution of new strains of disease causing agents, are of great concern to the global health community. Effective treatment of a disease entails the development of new pharmaceuticals or some potential source of novel drugs. Commonly used medicinal plants of our community could be an excellent source of drugs to fight off this problem. This study is focused on exploring the antimicrobial properties of the plants that are commonly being used as traditional medicines. The antimicrobial potential of four different plant extracts was screened against twelve pathogenic microorganisms and two reference bacterial strains. Methanolic extracts of\n                    <jats:italic>Oxalis corniculata<\/jats:italic>\n                    ,\n                    <jats:italic>Artemisia vulgaris<\/jats:italic>\n                    ,\n                    <jats:italic>Cinnamomum tamala<\/jats:italic>\n                    , and\n                    <jats:italic>Ageratina adenophora<\/jats:italic>\n                    were subjected to a test of their antimicrobial properties by agar well diffusion method. The result indicated that most of the extracts exhibited antimicrobial properties. The highest potential was observed in the extract of\n                    <jats:italic>O. corniculata<\/jats:italic>\n                    against\n                    <jats:italic>Escherichia coli, Salmonella Typhi,<\/jats:italic>\n                    MDR\n                    <jats:italic>Salmonella Typhi, Klebsiella pneumoniae,<\/jats:italic>\n                    and\n                    <jats:italic>Citrobacter koseri<\/jats:italic>\n                    with zone of inhibition (ZOI) of 17 mm, 13 mm, 16 mm, 11 mm, and 12 mm, respectively.\n                    <jats:italic>Oxalis corniculata<\/jats:italic>\n                    also showed the highest MIC against test organisms. The methanolic extract of\n                    <jats:italic>Artemisia vulgaris<\/jats:italic>\n                    ,\n                    <jats:italic>Cinnamomum tamala,<\/jats:italic>\n                    and\n                    <jats:italic>Ageratina adenophora<\/jats:italic>\n                    showed efficacy against\n                    <jats:italic>Staphylococcus aureus. Ageratina adenophora<\/jats:italic>\n                    also showed antifungal activity against\n                    <jats:italic>Rhizopus<\/jats:italic>\n                    spp. The experiment confirmed the efficacy of some selected plant extracts as natural antimicrobials and suggested the possibility of employing them in drugs for the treatment of infectious diseases caused by the test organisms.\n                  <\/jats:p>","DOI":"10.1155\/2019\/1895340","type":"journal-article","created":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T21:02:14Z","timestamp":1554238934000},"page":"1-5","source":"Crossref","is-referenced-by-count":341,"title":["In Vitro Antimicrobial Activity of Some Medicinal Plants against Human Pathogenic Bacteria"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0381-7174","authenticated-orcid":true,"given":"Sarita","family":"Manandhar","sequence":"first","affiliation":[{"name":"Tri-Chandra Multiple College, Tribhuvan University, Kathmandu, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shisir","family":"Luitel","sequence":"additional","affiliation":[{"name":"Tri-Chandra Multiple College, Tribhuvan University, Kathmandu, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj Kumar","family":"Dahal","sequence":"additional","affiliation":[{"name":"Tri-Chandra Multiple College, Tribhuvan University, Kathmandu, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"5","key":"1","first-page":"482","volume":"132","year":"2010","journal-title":"Indian Journal of Medical Research"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1086\/595011"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2010.11.014"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1038\/nrd940"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/265425","volume":"2015","year":"2015","journal-title":"BioMed Research International"},{"key":"7","volume-title":"New antimicrobials of plant origin in. Perspectives on new crops and new uses","year":"1999"},{"key":"8","year":"2002"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1021\/jf0511244"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2005.02.028"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-6-35"},{"issue":"164","key":"12","volume":"13","year":"2013","journal-title":"BMC Complementary and Alternative Medicine"},{"key":"13","volume":"4, article 24","year":"2008","journal-title":"Journal of Ethnobiology and Ethnomedicine"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1186\/1746-4269-8-19"},{"key":"15","year":"2001"},{"key":"16","year":"2002"},{"key":"17","year":"2012"},{"key":"18","year":"2015"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1086\/499819"},{"issue":"1","key":"19","first-page":"72","volume":"1","year":"2006","journal-title":"myScience"},{"issue":"7","key":"20","volume":"5","year":"2016","journal-title":"International Journal of Science and Research"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.12.4.564"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.4172\/2161-0509.1000190"},{"key":"23","first-page":"70","volume":"42","year":"2006","journal-title":"Journal of Beijing Normal University"},{"key":"24","first-page":"42","volume":"23","year":"2008","journal-title":"Journal of Yunnan Agricultural University"},{"issue":"1","key":"25","first-page":"1","volume":"1","year":"2014","journal-title":"International Journal of Biosciences and Nanosciences"},{"issue":"6","key":"26","first-page":"1674","volume":"2","year":"2011","journal-title":"International Journal of Research in Ayurveda & Pharmacy"},{"issue":"2","key":"27","first-page":"121","volume":"3","year":"2014","journal-title":"Bulletin of Environment, Pharmacology and Life Sciences"}],"container-title":["Journal of Tropical Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jtm\/2019\/1895340.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jtm\/2019\/1895340.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jtm\/2019\/1895340.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T21:02:17Z","timestamp":1554238937000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/jtm\/2019\/1895340\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,2]]},"references-count":27,"alternative-id":["1895340","1895340"],"URL":"https:\/\/doi.org\/10.1155\/2019\/1895340","relation":{},"ISSN":["1687-9686","1687-9694"],"issn-type":[{"value":"1687-9686","type":"print"},{"value":"1687-9694","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,2]]}}}