{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:02:45Z","timestamp":1740164565157,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T00:00:00Z","timestamp":1555891200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Gastrointestinal Medicine"],"published-print":{"date-parts":[[2019,4,22]]},"abstract":"<jats:p><jats:italic>Background and Aims.<\/jats:italic> Ulcerative colitis (UC) is a superficial diffuse inflammation restricted to the colon and rectum. Inflammation within the small bowel may occur several years after a pancolectomy. The pathogenesis is unknown and seems to be different from Crohn\u2019s disease or other causes of diseases of the small intestine, but an association with colectomy due to UC is very likely.<jats:italic> Methods and Results.<\/jats:italic> We describe the case of a patient with a probable diagnosis of pan-UC accompanied by Sj\u00f6gren\u2019s syndrome and partial IgA deficiency, who developed enteritis after a restorative pancolectomy. For induction and maintenance of remission, the patient was successfully treated with mycofenolate mofetil (MMF) and vedolizumab (VDZ).<jats:italic> Conclusions.<\/jats:italic> We suggest that a previously refractory to standard therapy UC-related enteritis can be treated with combination MMF and VDZ.<\/jats:p>","DOI":"10.1155\/2019\/2091089","type":"journal-article","created":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T19:34:30Z","timestamp":1555961670000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["<i>\u03b1<\/i>4<i>\u03b2<\/i>7 Integrin Antagonist Vedolizumab for the Treatment of Refractory Ileitis"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5954-151X","authenticated-orcid":true,"given":"Rafa\u0142","family":"Filip","sequence":"first","affiliation":[{"name":"Department of Gastroenterology with IBD Unit of Clinical Hospital 2, University of Rzeszow, Lwowska 60, 35-301 Rzeszow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2483-7839","authenticated-orcid":true,"given":"B\u0142a\u017cej","family":"Goliat","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology with IBD Unit of Clinical Hospital 2, University of Rzeszow, Lwowska 60, 35-301 Rzeszow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma\u0142gorzata","family":"Dziechcia\u017c","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, Health Care Institute of PWSTE, Czarneckiego 16, 37-500 Jaroslaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"D\u0105browski","sequence":"additional","affiliation":[{"name":"Department of Rheumatology of Clinical Hospital 2, University of Rzeszow, Lwowska 60, 35-301 Rzeszow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micha\u0142","family":"Osuchowski","sequence":"additional","affiliation":[{"name":"Department of Pathology of Clinical Hospital 2, University of Rzeszow, Lwowska 60, 35-301 Rzeszow, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Paluszkiewicz","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Surgery, Institute of Haematology and Transfusion Medicine in Warsaw, Indiry Ghandi 14, 02-776 Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2014.02.019"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e3182582c1d"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx140"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2006.00954.x"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2005.00278.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e32831bc400"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2008.02.031"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.72.850.499"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/254319"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-007-0284-8"},{"key":"11","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1002\/ibd.20409","volume":"14","year":"2008","journal-title":"Inflammatory Bowel Diseases"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-017-2761-4"},{"issue":"1","key":"13","volume":"4","year":"2017","journal-title":"BMJ Open Gastroenterology"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx090"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.2147\/CEG.S179418"}],"container-title":["Case Reports in Gastrointestinal Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2019\/2091089.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2019\/2091089.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crigm\/2019\/2091089.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T19:34:32Z","timestamp":1555961672000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crigm\/2019\/2091089\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,22]]},"references-count":15,"alternative-id":["2091089","2091089"],"URL":"https:\/\/doi.org\/10.1155\/2019\/2091089","relation":{},"ISSN":["2090-6528","2090-6536"],"issn-type":[{"type":"print","value":"2090-6528"},{"type":"electronic","value":"2090-6536"}],"subject":[],"published":{"date-parts":[[2019,4,22]]}}}