{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T01:36:33Z","timestamp":1791941793391,"version":"4.3.4"},"reference-count":48,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T00:00:00Z","timestamp":1560729600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011665","name":"Deanship of Scientific Research, King Saud University","doi-asserted-by":"publisher","award":["RG-1440-100"],"award-info":[{"award-number":["RG-1440-100"]}],"id":[{"id":"10.13039\/501100011665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2019,6,17]]},"abstract":"<jats:p>This study investigated the phytochemical characteristics and antioxidant activity in leaves, roots, stem, flower, and seed parts of<jats:italic> Datura alba (D. alba). <\/jats:italic>The study also assessed the heavy metal (Cr, Mn, Zn, and Cu) accumulation in each part of the plant<jats:italic>. <\/jats:italic>Among the phytochemicals, alkaloids were found only in leaves while tannins, flavonoids, and phenols were present in all parts of the plant. For antioxidant activity, free radical scavenging assay for 2,2-diphenyl-1-picrylhydrazyl (DPPH) was performed using ascorbic acid as the standard. Higher activity was shown by stem extract in methanol and leaf extract in n-hexane, ethyl acetate, and chloroform. Furthermore, all the target heavy metals were detected in all plant sections with the highest concentration of Zn in leaves and Cu in stem, root, flower, and seed. Due to stronger antioxidant potential and phytochemical composition,<jats:italic> D. alba<\/jats:italic> could prove as valuable prospect in pharmaceutical formulations by taking part in the antioxidant defense system against generation of free radicals.<\/jats:p>","DOI":"10.1155\/2019\/2403718","type":"journal-article","created":{"date-parts":[[2019,6,17]],"date-time":"2019-06-17T19:30:43Z","timestamp":1560799843000},"page":"1-8","source":"Crossref","is-referenced-by-count":35,"title":["Antioxidant Potential, Phytochemicals Composition, and Metal Contents of<i> Datura alba<\/i>"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7535-6720","authenticated-orcid":true,"given":"Waliullah","family":"Khan","sequence":"first","affiliation":[{"name":"Department of Chemistry, Abdul Wali Khan University, Mardan, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidra","family":"Subhan","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Abdul Wali Khan University, Mardan, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilawar Farhan","family":"Shams","sequence":"additional","affiliation":[{"name":"Department of Environmental Sciences, Abdul Wali Khan University, Mardan, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahib Gul","family":"Afridi","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Abdul Wali Khan University, Mardan, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5753-3834","authenticated-orcid":true,"given":"Riaz","family":"Ullah","sequence":"additional","affiliation":[{"name":"Medicinal, Aromatic and Poisonous Plants Research Center (MAPRC), College of Pharmacy, King Saud University, P.O. 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