{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:49:13Z","timestamp":1790804953442,"version":"4.1.0"},"reference-count":45,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T00:00:00Z","timestamp":1569283200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Transplantation"],"published-print":{"date-parts":[[2019,9,24]]},"abstract":"<jats:p>Surgical site infections (SSI) of the abdominal wall in renal transplant recipients can on occasion require management with negative pressure wound therapy (NPWT). This is often successful, with a low risk of further complications. However, we describe three cases in which persistent or recurrent surgical site sepsis occurred, whilst NPWT was being deployed in adults with either wound dehiscence or initial SSI. This type of complication in the setting of NPWT has not been previously described in renal transplant recipients. Our case series demonstrates that in immunosuppressed transplant recipients, there may be ineffective microbial or bacterial bioburden clearance associated with the NPWT, which can lead to further infections. Hence recognition for infections in renal transplant patients undergoing treatment with NPWT is vital; furthermore, aggressive management of sepsis control with early debridement, antimicrobial use, and reassessment of the use of wound dressing is necessary to reduce the morbidity associated with surgical site infections and NPWT.<\/jats:p>","DOI":"10.1155\/2019\/2452857","type":"journal-article","created":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T19:46:25Z","timestamp":1569354385000},"page":"1-6","source":"Crossref","is-referenced-by-count":3,"title":["Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2231-660X","authenticated-orcid":true,"given":"Susanna","family":"Lam","sequence":"first","affiliation":[{"name":"Royal Prince Alfred Hospital, Department of Transplantation Services, Sydney, Australia"},{"name":"The University of Sydney, Faculty of Medicine and Health, Edward Ford Building, Fisher Road, NSW 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ngee-Soon","family":"Lau","sequence":"additional","affiliation":[{"name":"Royal Prince Alfred Hospital, Department of Transplantation Services, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome Martin","family":"Laurence","sequence":"additional","affiliation":[{"name":"Royal Prince Alfred Hospital, Department of Transplantation Services, Sydney, Australia"},{"name":"The University of Sydney, Faculty of Medicine and Health, Edward Ford Building, Fisher Road, NSW 2006, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah Jean","family":"Verran","sequence":"additional","affiliation":[{"name":"Royal Prince Alfred Hospital, Department of Transplantation Services, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200112270-00009"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2015.03.046"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2014.77"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1797.2012.01621.x"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181b4ee9a"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/ajhp\/55.8.777"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s10029-005-0325-y"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.7182\/pit2015812"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000072016.13090.4E"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000227675.63744.af"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1067-1927.2004.12105.x"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0b013e3181a2e2b6"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009261.pub3"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1097\/01.sap.0000111861.75927.4d"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2010.00756.x"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1177\/1457496918818979"},{"issue":"1","key":"17","first-page":"4","volume":"5","year":"2007","journal-title":"Kathmandu University Medical Journal"},{"issue":"4","key":"18","first-page":"1199","volume":"38","year":"2014","journal-title":"Collegium Antropologicum"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/742161"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03237.x"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.5500\/wjt.v6.i4.767"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-019-0468-x"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000084400.53464.02"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1097\/01.bsd.0000133493.32503.d3"},{"issue":"5","key":"26","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1097\/00000637-200111000-00014","volume":"47","year":"2001","journal-title":"Annals of Plastic Surgery"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S66117"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000259773.52889.68"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2008.12.029"},{"issue":"2","key":"31","first-page":"32","volume":"22","year":"2010","journal-title":"Wounds"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2017.05.027"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199706000-00001"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2013.0510"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2010.00686.x"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.3109\/2000656x.2012.748667"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2012.156"},{"issue":"24","key":"38","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1056\/NEJM199806113382407","volume":"338","year":"1998","journal-title":"New England Journal of Medicine"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.5604\/01.3001.0012.1751"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.901884"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-86502012001200007"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12062"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-016-2600-z"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1007\/s10029-017-1691-y"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12183"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-481X.2009.00628.x"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12958"}],"container-title":["Case Reports in Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crit\/2019\/2452857.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crit\/2019\/2452857.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crit\/2019\/2452857.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T19:46:27Z","timestamp":1569354387000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crit\/2019\/2452857\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,24]]},"references-count":45,"alternative-id":["2452857","2452857"],"URL":"https:\/\/doi.org\/10.1155\/2019\/2452857","relation":{},"ISSN":["2090-6943","2090-6951"],"issn-type":[{"value":"2090-6943","type":"print"},{"value":"2090-6951","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,24]]}}}