{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:46:00Z","timestamp":1790696760786,"version":"4.1.0"},"reference-count":52,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T00:00:00Z","timestamp":1564012800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Contrast Media &amp; Molecular Imaging"],"published-print":{"date-parts":[[2019,7,25]]},"abstract":"<jats:p><jats:italic>Objectives<\/jats:italic>. The aim of this study is to explore the textural features that may identify the morphological changes in the lymphoma region and predict the prognosis of patients with primary renal lymphoma (PRL) and primary adrenal lymphoma (PAL). <jats:italic>Methods<\/jats:italic>. This retrospective study comprised nineteen non-Hodgkin\u2019s lymphoma (NHL) patients undergoing <jats:sup>18<\/jats:sup>F-FDG-PET\/CT at West China Hospital from December 2013 to May 2017. <jats:sup>18<\/jats:sup>F-FDG-PET images were reviewed independently by two board certificated radiologists of nuclear medicine, and the texture features were extracted from LifeX packages. The prognostic value of PET FDG-uptake parameters, patients\u2019 baseline characteristics, and textural parameters were analyzed using Kaplan\u2013Meier analysis. Cox regression analysis was used to identify the independent prognostic factors among the imaging and clinical features. <jats:italic>Results<\/jats:italic>. The overall survival of included patients was 18.84\u2009\u00b1\u200913.40 (mean\u2009\u00b1\u2009SD) months. Univariate Cox analyses found that the tumor stage, GLCM (gray-level co-occurrence matrix) entropy, GLZLM_GLNU (gray-level nonuniformity), and GLZLM_ZLNU (zone length nonuniformity), values were significant predictors for OS. Among them, GLRLM_RLNU \u2265216.6 demonstrated association with worse OS at multivariate analysis (HR 9.016, 95% CI 1.041\u201378.112, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.046<\/mml:mn><\/mml:mrow><\/mml:math>). <jats:italic>Conclusions<\/jats:italic>. The texture analysis of <jats:sup>18<\/jats:sup>F-FDG-PET images could potentially serve as a noninvasive strategy to predict the overall survival of patients with PRL and PAL.<\/jats:p>","DOI":"10.1155\/2019\/2641627","type":"journal-article","created":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T19:30:56Z","timestamp":1564083056000},"page":"1-9","source":"Crossref","is-referenced-by-count":19,"title":["Prognostic Value of Functional Parameters of <sup>18<\/sup>F-FDG-PET Images in Patients with Primary Renal\/Adrenal Lymphoma"],"prefix":"10.1155","volume":"2019","author":[{"given":"Manni","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Biotherapy, State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenpeng","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Biotherapy, State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sha","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Biotherapy, State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9148-5001","authenticated-orcid":true,"given":"Xuelei","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Biotherapy, State Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"9","key":"1","first-page":"584","volume":"18","year":"2008","journal-title":"Journal of the College of Physicians and Surgeons\u2014Pakistan: JCPSP"},{"key":"2","first-page":"85","volume-title":"World health organization classifcation of tumours","year":"2004"},{"issue":"1","key":"3","first-page":"44","volume":"74","year":"2002","journal-title":"Archivio Italiano di Urologia, Andrologia: Organo Ufficiale [di] Societa Italiana di Ecografia Urologica e Nefrologica"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19950501)75:9<2258::aid-cncr2820750911>3.0.co;2-s"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870801)60:3<386::aid-cncr2820600317>3.0.co;2-4"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.5414\/CNCS108955"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh250"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-013-1812-3"},{"issue":"5","key":"9","first-page":"221","volume":"13","year":"2008","journal-title":"European Journal of Medical Research"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2006.08.2305"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/01.rlu.0000155983.46815.1c"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/mnm.0b013e32833310fa"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.4158\/ep14471.or"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.5761\/atcs.ra.12.01954"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-011-1834-9"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-016-3316-6"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.112.119289"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1109\/83.725367"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.a4285"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2005.02.009"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2008.02.002"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-011-1845-6"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.110.082404"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2012.10.017"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-013-2486-8"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/61\/2\/906"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-015-3681-8"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.114.144055"},{"key":"29","year":"2016"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.15.15864"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-014-2961-x"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.111.099127"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(1950)3:1<32::aid-cncr2820030106>3.0.co;2-3"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-016-4470-8"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-009-0719-7"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-016-3506-2"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20591"},{"issue":"6","key":"38","first-page":"1023","volume":"61","year":"1977","journal-title":"Cancer Treatment Reports"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(12)60035-x"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2008.03.005"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2013.54.8800"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.4274\/tjh.2012.0125"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1097\/rlu.0000000000000867"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.113.133389"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-14-896"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms5644"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20160665"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2013.53.5229"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-013-2686-2"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1007\/s11307-009-0259-3"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2009.22.4089"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2323030985"}],"container-title":["Contrast Media &amp; Molecular Imaging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmi\/2019\/2641627.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmi\/2019\/2641627.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmi\/2019\/2641627.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T19:30:59Z","timestamp":1564083059000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cmmi\/2019\/2641627\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,25]]},"references-count":52,"alternative-id":["2641627","2641627"],"URL":"https:\/\/doi.org\/10.1155\/2019\/2641627","relation":{},"ISSN":["1555-4309","1555-4317"],"issn-type":[{"value":"1555-4309","type":"print"},{"value":"1555-4317","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,25]]}}}