{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:02:05Z","timestamp":1740164525498,"version":"3.37.3"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2019,4,10]],"date-time":"2019-04-10T00:00:00Z","timestamp":1554854400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2019,4,10]]},"abstract":"<jats:p>A 65-year-old male with a history of ischemic strokes, seizures, and subarachnoid hemorrhage presented with a 4-week history of progressive diplopia, vertigo, nausea, and vomiting. Magnetic resonance imaging (MRI) revealed a <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn>2.5<\/mml:mn><mml:mo>\u00d7<\/mml:mo><mml:mn>1.8<\/mml:mn><mml:mo>\u00d7<\/mml:mo><mml:mn>1.7<\/mml:mn><\/mml:math> cm posterior fossa mass arising from the roof of the 4<jats:sup>th<\/jats:sup> ventricle extending into the cerebellar vermis. Posterior fossa craniotomy with stereotactic biopsy confirmed a locally invasive diffuse large B-cell lymphoma (DLBCL). Primary central nervous system lymphoma (PCNSL) arising from the 4<jats:sup>th<\/jats:sup> ventricle is a rare extranodal manifestation of non-Hodgkin lymphoma (NHL), with few cases documented in the literature. Review of available cases lends support that lymphoma arising from the 4<jats:sup>th<\/jats:sup> ventricle has a variable clinical presentation, occurs most commonly in immunocompetent males, and should be on the differential of any immunocompetent adult presenting with a posterior fossa mass. Optimal treatment modalities are based largely on phase 2 clinical trials, and recommended guidelines regardless of anatomic location should be adhered to.<\/jats:p>","DOI":"10.1155\/2019\/2671794","type":"journal-article","created":{"date-parts":[[2019,4,10]],"date-time":"2019-04-10T20:03:55Z","timestamp":1554926635000},"page":"1-7","source":"Crossref","is-referenced-by-count":2,"title":["Primary CNS Lymphoma Arising from the 4<sup>th<\/sup> Ventricle: A Case Report and Review of the Literature"],"prefix":"10.1155","volume":"2019","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3382-4877","authenticated-orcid":true,"given":"Ava","family":"Brozovich","sequence":"first","affiliation":[{"name":"Texas A&M University College of Medicine, 8441 Riverside Parkway, Bryan, TX 77807, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald","family":"Ewing","sequence":"additional","affiliation":[{"name":"Texas A&M University College of Medicine, 8441 Riverside Parkway, 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